1Y7I
Structural and biochemical studies identify tobacco SABP2 as a methylsalicylate esterase and further implicate it in plant innate immunity, Northeast Structural Genomics Target AR2241
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0009694 | biological_process | jasmonic acid metabolic process |
| A | 0009696 | biological_process | salicylic acid metabolic process |
| A | 0009862 | biological_process | systemic acquired resistance, salicylic acid mediated signaling pathway |
| A | 0016298 | molecular_function | lipase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0045087 | biological_process | innate immune response |
| A | 0080030 | molecular_function | methyl indole-3-acetate esterase activity |
| A | 0080031 | molecular_function | methyl salicylate esterase activity |
| A | 0080032 | molecular_function | methyl jasmonate esterase activity |
| B | 0009694 | biological_process | jasmonic acid metabolic process |
| B | 0009696 | biological_process | salicylic acid metabolic process |
| B | 0009862 | biological_process | systemic acquired resistance, salicylic acid mediated signaling pathway |
| B | 0016298 | molecular_function | lipase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0045087 | biological_process | innate immune response |
| B | 0080030 | molecular_function | methyl indole-3-acetate esterase activity |
| B | 0080031 | molecular_function | methyl salicylate esterase activity |
| B | 0080032 | molecular_function | methyl jasmonate esterase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SAL A 501 |
| Chain | Residue |
| A | ALA13 |
| A | SER81 |
| A | LEU82 |
| A | PHE107 |
| A | TYR122 |
| A | TRP131 |
| A | PHE151 |
| A | HIS238 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SAL A 502 |
| Chain | Residue |
| A | HIS158 |
| A | LYS159 |
| A | HOH562 |
| B | LEU253 |
| B | GLU254 |
| B | HIS257 |
| A | LEU132 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SAL B 503 |
| Chain | Residue |
| B | ALA13 |
| B | SER81 |
| B | LEU82 |
| B | PHE107 |
| B | TYR122 |
| B | PHE151 |
| B | HIS238 |
Functional Information from PROSITE/UniProt
| site_id | PS00120 |
| Number of Residues | 10 |
| Details | LIPASE_SER Lipases, serine active site. VILVGHSLGG |
| Chain | Residue | Details |
| A | VAL75-GLY84 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: Acyl-ester intermediate => ECO:0000269|PubMed:15668381, ECO:0000269|PubMed:17916738 |
| Chain | Residue | Details |
| A | SER81 | |
| B | SER81 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | ACT_SITE: Charge relay system => ECO:0000269|PubMed:15668381 |
| Chain | Residue | Details |
| A | ASP210 | |
| B | ASP210 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | ACT_SITE: Charge relay system => ECO:0000269|PubMed:17916738 |
| Chain | Residue | Details |
| A | HIS238 | |
| B | HIS238 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15668381, ECO:0007744|PDB:1Y7I |
| Chain | Residue | Details |
| A | ALA13 | |
| B | HIS238 | |
| B | LEU253 | |
| B | HIS257 | |
| A | SER81 | |
| A | LYS159 | |
| A | HIS238 | |
| A | LEU253 | |
| A | HIS257 | |
| B | ALA13 | |
| B | SER81 | |
| B | LYS159 |
