Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1Y7H

Structural and biochemical studies identify tobacco SABP2 as a methylsalicylate esterase and further implicate it in plant innate immunity, Northeast Structural Genomics Target AR2241

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0009694	biological_process	jasmonic acid metabolic process
A	0009696	biological_process	salicylic acid metabolic process
A	0009862	biological_process	systemic acquired resistance, salicylic acid mediated signaling pathway
A	0016298	molecular_function	lipase activity
A	0016787	molecular_function	hydrolase activity
A	0080030	molecular_function	methyl indole-3-acetate esterase activity
A	0080031	molecular_function	methyl salicylate esterase activity
A	0080032	molecular_function	methyl jasmonate esterase activity
B	0009694	biological_process	jasmonic acid metabolic process
B	0009696	biological_process	salicylic acid metabolic process
B	0009862	biological_process	systemic acquired resistance, salicylic acid mediated signaling pathway
B	0016298	molecular_function	lipase activity
B	0016787	molecular_function	hydrolase activity
B	0080030	molecular_function	methyl indole-3-acetate esterase activity
B	0080031	molecular_function	methyl salicylate esterase activity
B	0080032	molecular_function	methyl jasmonate esterase activity
C	0009694	biological_process	jasmonic acid metabolic process
C	0009696	biological_process	salicylic acid metabolic process
C	0009862	biological_process	systemic acquired resistance, salicylic acid mediated signaling pathway
C	0016298	molecular_function	lipase activity
C	0016787	molecular_function	hydrolase activity
C	0080030	molecular_function	methyl indole-3-acetate esterase activity
C	0080031	molecular_function	methyl salicylate esterase activity
C	0080032	molecular_function	methyl jasmonate esterase activity
D	0009694	biological_process	jasmonic acid metabolic process
D	0009696	biological_process	salicylic acid metabolic process
D	0009862	biological_process	systemic acquired resistance, salicylic acid mediated signaling pathway
D	0016298	molecular_function	lipase activity
D	0016787	molecular_function	hydrolase activity
D	0080030	molecular_function	methyl indole-3-acetate esterase activity
D	0080031	molecular_function	methyl salicylate esterase activity
D	0080032	molecular_function	methyl jasmonate esterase activity
E	0009694	biological_process	jasmonic acid metabolic process
E	0009696	biological_process	salicylic acid metabolic process
E	0009862	biological_process	systemic acquired resistance, salicylic acid mediated signaling pathway
E	0016298	molecular_function	lipase activity
E	0016787	molecular_function	hydrolase activity
E	0080030	molecular_function	methyl indole-3-acetate esterase activity
E	0080031	molecular_function	methyl salicylate esterase activity
E	0080032	molecular_function	methyl jasmonate esterase activity
F	0009694	biological_process	jasmonic acid metabolic process
F	0009696	biological_process	salicylic acid metabolic process
F	0009862	biological_process	systemic acquired resistance, salicylic acid mediated signaling pathway
F	0016298	molecular_function	lipase activity
F	0016787	molecular_function	hydrolase activity
F	0080030	molecular_function	methyl indole-3-acetate esterase activity
F	0080031	molecular_function	methyl salicylate esterase activity
F	0080032	molecular_function	methyl jasmonate esterase activity
G	0009694	biological_process	jasmonic acid metabolic process
G	0009696	biological_process	salicylic acid metabolic process
G	0009862	biological_process	systemic acquired resistance, salicylic acid mediated signaling pathway
G	0016298	molecular_function	lipase activity
G	0016787	molecular_function	hydrolase activity
G	0080030	molecular_function	methyl indole-3-acetate esterase activity
G	0080031	molecular_function	methyl salicylate esterase activity
G	0080032	molecular_function	methyl jasmonate esterase activity
H	0009694	biological_process	jasmonic acid metabolic process
H	0009696	biological_process	salicylic acid metabolic process
H	0009862	biological_process	systemic acquired resistance, salicylic acid mediated signaling pathway
H	0016298	molecular_function	lipase activity
H	0016787	molecular_function	hydrolase activity
H	0080030	molecular_function	methyl indole-3-acetate esterase activity
H	0080031	molecular_function	methyl salicylate esterase activity
H	0080032	molecular_function	methyl jasmonate esterase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SCN A 291

Chain	Residue
A	THR147
A	SER180
A	LEU181
A	PHE182
A	MSE183
A	GLU184

site_id	AC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SCN B 292

Chain	Residue
B	MSE183
B	HOH293
B	THR147
B	MSE149
B	LEU181

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SCN C 293

Chain	Residue
C	THR147
C	MSE149
C	SER180
C	LEU181
C	PHE182
C	MSE183
C	GLU184

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SCN D 294

Chain	Residue
D	THR147
D	SER148
D	MSE149
D	LEU181
D	MSE183
D	HOH314

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SCN E 295

Chain	Residue
E	THR147
E	SER180
E	LEU181
E	PHE182
E	MSE183

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SCN F 296

Chain	Residue
F	THR147
F	LEU181
F	MSE183

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SCN G 297

Chain	Residue
G	PHE136
G	THR147
G	MSE149
G	LEU181
G	PHE182
G	MSE183
G	GLU184

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SCN H 298

Chain	Residue
H	THR147
H	LEU181
H	PHE182
H	MSE183

Functional Information from PROSITE/UniProt

site_id	PS00120
Number of Residues	10
Details	LIPASE_SER Lipases, serine active site. VILVGHSLGG

Chain	Residue	Details
A	VAL75-GLY84

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	8
Details	Active site: {"description":"Acyl-ester intermediate","evidences":[{"source":"PubMed","id":"15668381","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17916738","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	8
Details	Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"15668381","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15668381","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1Y7I","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1c4x

Chain	Residue	Details
A	SER81
A	HIS238
A	ASP210

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1c4x

Chain	Residue	Details
B	SER81
B	HIS238
B	ASP210

site_id	CSA3
Number of Residues	3
Details	Annotated By Reference To The Literature 1c4x

Chain	Residue	Details
C	SER81
C	HIS238
C	ASP210

site_id	CSA4
Number of Residues	3
Details	Annotated By Reference To The Literature 1c4x

Chain	Residue	Details
D	SER81
D	HIS238
D	ASP210

site_id	CSA5
Number of Residues	3
Details	Annotated By Reference To The Literature 1c4x

Chain	Residue	Details
E	SER81
E	HIS238
E	ASP210

site_id	CSA6
Number of Residues	3
Details	Annotated By Reference To The Literature 1c4x

Chain	Residue	Details
F	SER81
F	HIS238
F	ASP210

site_id	CSA7
Number of Residues	3
Details	Annotated By Reference To The Literature 1c4x

Chain	Residue	Details
G	SER81
G	HIS238
G	ASP210

site_id	CSA8
Number of Residues	3
Details	Annotated By Reference To The Literature 1c4x

Chain	Residue	Details
H	SER81
H	HIS238
H	ASP210

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)