1Y5Y

Structure of the tetrahydromethanopterin dependent formaldehyde-activating enzyme (Fae) from Methylobacterium extorquens AM1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005737	cellular_component	cytoplasm
A	0006730	biological_process	one-carbon metabolic process
A	0009636	biological_process	response to toxic substance
A	0016051	biological_process	carbohydrate biosynthetic process
A	0016829	molecular_function	lyase activity
A	0016840	molecular_function	carbon-nitrogen lyase activity
A	0046294	biological_process	formaldehyde catabolic process
B	0005737	cellular_component	cytoplasm
B	0006730	biological_process	one-carbon metabolic process
B	0009636	biological_process	response to toxic substance
B	0016051	biological_process	carbohydrate biosynthetic process
B	0016829	molecular_function	lyase activity
B	0016840	molecular_function	carbon-nitrogen lyase activity
B	0046294	biological_process	formaldehyde catabolic process
C	0005737	cellular_component	cytoplasm
C	0006730	biological_process	one-carbon metabolic process
C	0009636	biological_process	response to toxic substance
C	0016051	biological_process	carbohydrate biosynthetic process
C	0016829	molecular_function	lyase activity
C	0016840	molecular_function	carbon-nitrogen lyase activity
C	0046294	biological_process	formaldehyde catabolic process
D	0005737	cellular_component	cytoplasm
D	0006730	biological_process	one-carbon metabolic process
D	0009636	biological_process	response to toxic substance
D	0016051	biological_process	carbohydrate biosynthetic process
D	0016829	molecular_function	lyase activity
D	0016840	molecular_function	carbon-nitrogen lyase activity
D	0046294	biological_process	formaldehyde catabolic process
E	0005737	cellular_component	cytoplasm
E	0006730	biological_process	one-carbon metabolic process
E	0009636	biological_process	response to toxic substance
E	0016051	biological_process	carbohydrate biosynthetic process
E	0016829	molecular_function	lyase activity
E	0016840	molecular_function	carbon-nitrogen lyase activity
E	0046294	biological_process	formaldehyde catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CA C 201

Chain	Residue
A	ASN44
B	ASN1044
C	ASN2044
C	LYS2046
D	ASN3044
E	ASN4044
E	LYS4046

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site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA C 202

Chain	Residue
E	ARG4144
C	HOH540
C	GLN2143

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE NA E 203

Chain	Residue
C	ARG2144
C	GLU2149
E	GLN4143

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	ACT_SITE: Proton donor

Chain	Residue	Details
A	ILE23
B	ILE1023
C	ILE2023
D	ILE3023
E	ILE4023

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site_id	SWS_FT_FI2
Number of Residues	25
Details	BINDING:

Chain	Residue	Details
A	LEU25
B	HIS1089
C	LEU2025
C	ALA2054
C	VAL2072
C	ILE2074
C	HIS2089
D	LEU3025
D	ALA3054
D	VAL3072
D	ILE3074
A	ALA54
D	HIS3089
E	LEU4025
E	ALA4054
E	VAL4072
E	ILE4074
E	HIS4089
A	VAL72
A	ILE74
A	HIS89
B	LEU1025
B	ALA1054
B	VAL1072
B	ILE1074

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