Loading
PDBj
MenuPDBj@FacebookPDBj@X(formerly Twitter)PDBj@BlueSkyPDBj@YouTubewwPDB FoundationwwPDBDonate
RCSB PDBPDBeBMRBAdv. SearchSearch help

1Y4S

Conformation rearrangement of heat shock protein 90 upon ADP binding

Functional Information from GO Data
ChainGOidnamespacecontents
A0005515molecular_functionprotein binding
A0005524molecular_functionATP binding
A0005737cellular_componentcytoplasm
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006457biological_processprotein folding
A0006974biological_processDNA damage response
A0009408biological_processresponse to heat
A0016887molecular_functionATP hydrolysis activity
A0018106biological_processpeptidyl-histidine phosphorylation
A0042802molecular_functionidentical protein binding
A0042803molecular_functionprotein homodimerization activity
A0043093biological_processFtsZ-dependent cytokinesis
A0044183molecular_functionprotein folding chaperone
A0051082molecular_functionunfolded protein binding
A0051087molecular_functionprotein-folding chaperone binding
A0140662molecular_functionATP-dependent protein folding chaperone
B0005515molecular_functionprotein binding
B0005524molecular_functionATP binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0005886cellular_componentplasma membrane
B0006457biological_processprotein folding
B0006974biological_processDNA damage response
B0009408biological_processresponse to heat
B0016887molecular_functionATP hydrolysis activity
B0018106biological_processpeptidyl-histidine phosphorylation
B0042802molecular_functionidentical protein binding
B0042803molecular_functionprotein homodimerization activity
B0043093biological_processFtsZ-dependent cytokinesis
B0044183molecular_functionprotein folding chaperone
B0051082molecular_functionunfolded protein binding
B0051087molecular_functionprotein-folding chaperone binding
B0140662molecular_functionATP-dependent protein folding chaperone
Functional Information from PDB Data
site_idAC1
Number of Residues3
DetailsBINDING SITE FOR RESIDUE MG A 703
ChainResidue
AGLU34
AASN38
AADP701

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE MG B 704
ChainResidue
BGLU34
BASN38
BHIS255
BADP702

site_idAC3
Number of Residues9
DetailsBINDING SITE FOR RESIDUE ADP A 701
ChainResidue
AMET85
AHIS93
AGLY126
APHE127
ATHR174
AHIS255
AMG703
AASN38
AASP80

site_idAC4
Number of Residues8
DetailsBINDING SITE FOR RESIDUE ADP B 702
ChainResidue
BASN38
BALA42
BASP80
BHIS93
BPHE127
BTHR174
BHIS255
BMG704

Functional Information from PROSITE/UniProt
site_idPS00298
Number of Residues10
DetailsHSP90 Heat shock hsp90 proteins family signature. YsNKEIFLRE
ChainResidueDetails
ATYR25-GLU34

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues10
DetailsBinding site: {"evidences":[{"source":"PubMed","id":"15837196","evidenceCode":"ECO:0000269"}]}
ChainResidueDetails

251174

PDB entries from 2026-03-25

PDB statisticsPDBj update infoContact PDBjnumon