1Y4E

NMR structure of transmembrane segment IV of the NHE1 isoform of the Na+/H+ exchanger

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0006814	biological_process	sodium ion transport
A	0006885	biological_process	regulation of pH
A	0015385	molecular_function	sodium:proton antiporter activity
A	0016020	cellular_component	membrane
A	0055085	biological_process	transmembrane transport

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	17
Details	TRANSMEM: Helical; Name=3 => ECO:0000269|PubMed:34108458, ECO:0007744|PDB:7DSW

Chain	Residue	Details
A	ASP159-PHE176

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site_id	SWS_FT_FI2
Number of Residues	1
Details	SITE: Channel pore-lining => ECO:0000305

Chain	Residue	Details
A	PHE161

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