1XZX

Thyroxine-Thyroid Hormone Receptor Interactions

Functional Information from GO Data

Chain	GOid	namespace	contents
X	0003677	molecular_function	DNA binding
X	0004879	molecular_function	nuclear receptor activity
X	0006355	biological_process	regulation of DNA-templated transcription

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CAC X 501

Chain	Residue
X	CYS294

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site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CAC X 502

Chain	Residue
X	CYS298
X	GLU299

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site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CAC X 503

Chain	Residue
X	HOH54
X	HIS210
X	CYS298

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site_id	AC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CAC X 504

Chain	Residue
X	CYS388
X	ARG391

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site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CAC X 505

Chain	Residue
X	ASP427
X	CYS434
X	HOH37

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site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE CAC X 506

Chain	Residue
X	CYS434

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site_id	AC7
Number of Residues	15
Details	BINDING SITE FOR RESIDUE T3 X 500

Chain	Residue
X	HOH38
X	PHE272
X	ILE275
X	ILE276
X	ALA279
X	ARG282
X	MET313
X	ARG316
X	THR329
X	LEU330
X	ASN331
X	LEU346
X	ILE353
X	HIS435
X	PHE455

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	3
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15466465","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1Y0X","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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