Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1XY3

Urate oxidase from aspergillus flavus complexed with guanine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004846	molecular_function	urate oxidase activity
A	0005777	cellular_component	peroxisome
A	0006144	biological_process	purine nucleobase metabolic process
A	0006145	biological_process	purine nucleobase catabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0019628	biological_process	urate catabolic process
B	0004846	molecular_function	urate oxidase activity
B	0005777	cellular_component	peroxisome
B	0006144	biological_process	purine nucleobase metabolic process
B	0006145	biological_process	purine nucleobase catabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0019628	biological_process	urate catabolic process
C	0004846	molecular_function	urate oxidase activity
C	0005777	cellular_component	peroxisome
C	0006144	biological_process	purine nucleobase metabolic process
C	0006145	biological_process	purine nucleobase catabolic process
C	0016491	molecular_function	oxidoreductase activity
C	0019628	biological_process	urate catabolic process
D	0004846	molecular_function	urate oxidase activity
D	0005777	cellular_component	peroxisome
D	0006144	biological_process	purine nucleobase metabolic process
D	0006145	biological_process	purine nucleobase catabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0019628	biological_process	urate catabolic process
E	0004846	molecular_function	urate oxidase activity
E	0005777	cellular_component	peroxisome
E	0006144	biological_process	purine nucleobase metabolic process
E	0006145	biological_process	purine nucleobase catabolic process
E	0016491	molecular_function	oxidoreductase activity
E	0019628	biological_process	urate catabolic process
F	0004846	molecular_function	urate oxidase activity
F	0005777	cellular_component	peroxisome
F	0006144	biological_process	purine nucleobase metabolic process
F	0006145	biological_process	purine nucleobase catabolic process
F	0016491	molecular_function	oxidoreductase activity
F	0019628	biological_process	urate catabolic process
G	0004846	molecular_function	urate oxidase activity
G	0005777	cellular_component	peroxisome
G	0006144	biological_process	purine nucleobase metabolic process
G	0006145	biological_process	purine nucleobase catabolic process
G	0016491	molecular_function	oxidoreductase activity
G	0019628	biological_process	urate catabolic process
H	0004846	molecular_function	urate oxidase activity
H	0005777	cellular_component	peroxisome
H	0006144	biological_process	purine nucleobase metabolic process
H	0006145	biological_process	purine nucleobase catabolic process
H	0016491	molecular_function	oxidoreductase activity
H	0019628	biological_process	urate catabolic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GUN A 900

Chain	Residue
A	PHE159
A	ARG176
A	VAL227
A	GLN228
B	ILE54
B	THR57

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GUN B 901

Chain	Residue
B	ARG176
B	VAL227
B	GLN228
A	ALA56
A	THR57
B	PHE159

site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GUN C 902

Chain	Residue
C	PHE159
C	ARG176
C	VAL227
C	GLN228
D	ILE54
D	ALA56
D	THR57

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GUN D 903

Chain	Residue
C	ILE54
C	THR57
D	PHE159
D	ARG176
D	VAL227
D	GLN228

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GUN E 904

Chain	Residue
E	PHE159
E	ARG176
E	VAL227
E	GLN228
F	THR57

site_id	AC6
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GUN F 905

Chain	Residue
E	ILE54
E	ALA56
E	THR57
F	PHE159
F	ARG176
F	VAL227
F	GLN228

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GUN G 906

Chain	Residue
G	PHE159
G	ARG176
G	VAL227
G	GLN228
H	ILE54
H	ALA56
H	THR57

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE GUN H 907

Chain	Residue
G	THR57
H	PHE159
H	ARG176
H	VAL227
H	GLN228

Functional Information from PROSITE/UniProt

site_id	PS00366
Number of Residues	28
Details	URICASE Uricase signature. LtVLKSTnSqFwgFlrdeYttLketwdR

Chain	Residue	Details
A	LEU149-ARG176

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	Active site: {"description":"Charge relay system","evidences":[{"source":"PubMed","id":"24466188","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"4N3M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9V","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9360612","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1R4S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1R51","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1WS2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FXL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IBA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ICQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZKA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZKB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3F2M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GKO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3LBG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3LD4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3P9F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OP6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OP9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FRC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9360612","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1R4S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3LBG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3LD4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9S","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9360612","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1R4S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1R51","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1WS3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XT4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XY3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IBA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ICQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZKA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZKB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3F2M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GKO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L8W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3P9F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OP6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OP9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FRC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI5
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9360612","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1R4S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1R51","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1WRR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1WS2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1WS3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XT4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XXJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XY3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IBA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ICQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZKA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZKB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3F2M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GKO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L8W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3LBG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3P9F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OP6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OP9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FRC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI6
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9360612","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1R4S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1R51","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1WRR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XT4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XXJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XY3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IBA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ICQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZKA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZKB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3F2M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GKO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L8W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3P9F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OP6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OP9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FRC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI7
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"9360612","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1R4S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1R51","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1WRR","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1WS2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XT4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XXJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1XY3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2FUB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IBA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2IC0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ICQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2PES","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZKA","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2ZKB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3BK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3CKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3F2M","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3GKO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3L8W","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3LBG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3LD4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3P9F","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PJK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK4","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK5","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PK8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKF","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKK","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKL","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKS","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKT","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PKU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLE","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLH","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLI","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLJ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3PLM","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9S","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4N9V","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OP6","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4OP9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"5FRC","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

site_id	SWS_FT_FI8
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PDB","id":"4CW2","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW3","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"4CW6","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1r51

Chain	Residue	Details
A	GLN228
A	ARG176

site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1r51

Chain	Residue	Details
B	GLN228
B	ARG176

site_id	CSA3
Number of Residues	2
Details	Annotated By Reference To The Literature 1r51

Chain	Residue	Details
C	GLN228
C	ARG176

site_id	CSA4
Number of Residues	2
Details	Annotated By Reference To The Literature 1r51

Chain	Residue	Details
D	GLN228
D	ARG176

site_id	CSA5
Number of Residues	2
Details	Annotated By Reference To The Literature 1r51

Chain	Residue	Details
E	GLN228
E	ARG176

site_id	CSA6
Number of Residues	2
Details	Annotated By Reference To The Literature 1r51

Chain	Residue	Details
F	GLN228
F	ARG176

site_id	CSA7
Number of Residues	2
Details	Annotated By Reference To The Literature 1r51

Chain	Residue	Details
G	GLN228
G	ARG176

site_id	CSA8
Number of Residues	2
Details	Annotated By Reference To The Literature 1r51

Chain	Residue	Details
H	GLN228
H	ARG176

site_id	MCSA1
Number of Residues	5
Details	M-CSA 118

Chain	Residue	Details
A	ARG14	hydrogen bond donor, proton acceptor, proton donor, proton relay
A	LYS61	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
A	THR180	electrostatic stabiliser
A	TYR232	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor
A	ILE260	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay

site_id	MCSA2
Number of Residues	5
Details	M-CSA 118

Chain	Residue	Details
B	ARG14	hydrogen bond donor, proton acceptor, proton donor, proton relay
B	LYS61	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
B	THR180	electrostatic stabiliser
B	TYR232	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor
B	ILE260	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay

site_id	MCSA3
Number of Residues	5
Details	M-CSA 118

Chain	Residue	Details
C	ARG14	hydrogen bond donor, proton acceptor, proton donor, proton relay
C	LYS61	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
C	THR180	electrostatic stabiliser
C	TYR232	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor
C	ILE260	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay

site_id	MCSA4
Number of Residues	5
Details	M-CSA 118

Chain	Residue	Details
D	ARG14	hydrogen bond donor, proton acceptor, proton donor, proton relay
D	LYS61	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
D	THR180	electrostatic stabiliser
D	TYR232	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor
D	ILE260	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay

site_id	MCSA5
Number of Residues	5
Details	M-CSA 118

Chain	Residue	Details
E	ARG14	hydrogen bond donor, proton acceptor, proton donor, proton relay
E	LYS61	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
E	THR180	electrostatic stabiliser
E	TYR232	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor
E	ILE260	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay

site_id	MCSA6
Number of Residues	5
Details	M-CSA 118

Chain	Residue	Details
F	ARG14	hydrogen bond donor, proton acceptor, proton donor, proton relay
F	LYS61	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
F	THR180	electrostatic stabiliser
F	TYR232	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor
F	ILE260	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay

site_id	MCSA7
Number of Residues	5
Details	M-CSA 118

Chain	Residue	Details
G	ARG14	hydrogen bond donor, proton acceptor, proton donor, proton relay
G	LYS61	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
G	THR180	electrostatic stabiliser
G	TYR232	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor
G	ILE260	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay

site_id	MCSA8
Number of Residues	5
Details	M-CSA 118

Chain	Residue	Details
H	ARG14	hydrogen bond donor, proton acceptor, proton donor, proton relay
H	LYS61	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay
H	THR180	electrostatic stabiliser
H	TYR232	electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor
H	ILE260	hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor, proton relay

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)