1XVQ
Crystal structure of thiol peroxidase from Mycobacterium tuberculosis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004601 | molecular_function | peroxidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005829 | cellular_component | cytosol |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0008379 | molecular_function | thioredoxin peroxidase activity |
| A | 0009274 | cellular_component | peptidoglycan-based cell wall |
| A | 0015036 | molecular_function | disulfide oxidoreductase activity |
| A | 0016209 | molecular_function | antioxidant activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016684 | molecular_function | oxidoreductase activity, acting on peroxide as acceptor |
| A | 0034599 | biological_process | cellular response to oxidative stress |
| A | 0045454 | biological_process | cell redox homeostasis |
| A | 0051409 | biological_process | response to nitrosative stress |
| A | 0051920 | molecular_function | peroxiredoxin activity |
| A | 0098754 | biological_process | detoxification |
| A | 0098869 | biological_process | cellular oxidant detoxification |
| A | 0140824 | molecular_function | thioredoxin-dependent peroxiredoxin activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE YT3 A 201 |
| Chain | Residue |
| A | GLU16 |
| A | GLU149 |
| A | YT3203 |
| A | HOH470 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE YT3 A 202 |
| Chain | Residue |
| A | ASP40 |
| A | ASP40 |
| A | ASP40 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE YT3 A 203 |
| Chain | Residue |
| A | YT3201 |
| A | HOH548 |
| A | GLU16 |
| A | GLU149 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NH4 A 301 |
| Chain | Residue |
| A | ASP56 |
| A | ASP56 |
| A | ALA88 |
| A | ALA88 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE NH4 A 302 |
| Chain | Residue |
| A | HOH509 |
| A | HOH509 |
| A | HOH509 |
Functional Information from PROSITE/UniProt
| site_id | PS01265 |
| Number of Residues | 12 |
| Details | TPX Tpx family signature. SkDLPFAqkRFC |
| Chain | Residue | Details |
| A | SER82-CYS93 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Cysteine sulfenic acid (-SOH) intermediate => ECO:0000250|UniProtKB:P0A862, ECO:0000255|HAMAP-Rule:MF_00269, ECO:0000305|PubMed:16884737 |
| Chain | Residue | Details |
| A | CYS60 |
