1XVG
soluble methane monooxygenase hydroxylase: bromoethanol soaked structure
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0006730 | biological_process | one-carbon metabolic process |
| A | 0015049 | molecular_function | methane monooxygenase [NAD(P)H] activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0006730 | biological_process | one-carbon metabolic process |
| B | 0015049 | molecular_function | methane monooxygenase [NAD(P)H] activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0004497 | molecular_function | monooxygenase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0006730 | biological_process | one-carbon metabolic process |
| C | 0015049 | molecular_function | methane monooxygenase [NAD(P)H] activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| D | 0004497 | molecular_function | monooxygenase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0006730 | biological_process | one-carbon metabolic process |
| D | 0015049 | molecular_function | methane monooxygenase [NAD(P)H] activity |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| E | 0004497 | molecular_function | monooxygenase activity |
| E | 0006730 | biological_process | one-carbon metabolic process |
| E | 0015049 | molecular_function | methane monooxygenase [NAD(P)H] activity |
| E | 0015947 | biological_process | methane metabolic process |
| F | 0004497 | molecular_function | monooxygenase activity |
| F | 0006730 | biological_process | one-carbon metabolic process |
| F | 0015049 | molecular_function | methane monooxygenase [NAD(P)H] activity |
| F | 0015947 | biological_process | methane metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FE A 528 |
| Chain | Residue |
| A | GLU114 |
| A | GLU144 |
| A | HIS147 |
| A | FE529 |
| A | BRJ3803 |
| A | HOH4001 |
| A | HOH4099 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE FE A 529 |
| Chain | Residue |
| A | GLU209 |
| A | GLU243 |
| A | HIS246 |
| A | FE528 |
| A | BRJ3803 |
| A | HOH4099 |
| A | GLN140 |
| A | GLU144 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FE B 528 |
| Chain | Residue |
| B | GLU114 |
| B | GLU144 |
| B | HIS147 |
| B | FE529 |
| B | BRJ3800 |
| B | HOH3816 |
| B | HOH3882 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FE B 529 |
| Chain | Residue |
| B | GLU144 |
| B | GLU209 |
| B | GLU243 |
| B | HIS246 |
| B | FE528 |
| B | BRJ3800 |
| B | HOH3816 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE CA C 1111 |
| Chain | Residue |
| C | GLU222 |
| C | HOH3818 |
| C | HOH3821 |
| C | HOH4022 |
| C | HOH4031 |
| C | HOH4077 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA C 1112 |
| Chain | Residue |
| C | ASP348 |
| C | HOH4056 |
| C | HOH4057 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 1162 |
| Chain | Residue |
| A | ASN527 |
| A | HOH3856 |
| A | HOH4029 |
| A | HOH4112 |
| B | SER428 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CA C 1218 |
| Chain | Residue |
| C | ASP376 |
| C | ASP378 |
| C | HOH4084 |
| site_id | AC9 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE BRJ B 3800 |
| Chain | Residue |
| B | LEU110 |
| B | GLU114 |
| B | ALA117 |
| B | GLU144 |
| B | PHE192 |
| B | GLU209 |
| B | FE528 |
| B | FE529 |
| B | HOH3816 |
| B | HOH4086 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BRJ B 3801 |
| Chain | Residue |
| B | VAL106 |
| B | MET184 |
| B | VAL285 |
| site_id | BC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE BRJ B 3802 |
| Chain | Residue |
| B | THR102 |
| B | MET288 |
| B | GLY293 |
| B | TYR347 |
| B | LEU361 |
| site_id | BC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE BRJ A 3803 |
| Chain | Residue |
| A | LEU110 |
| A | GLU114 |
| A | ALA117 |
| A | GLU144 |
| A | GLU209 |
| A | FE528 |
| A | FE529 |
| A | HOH4001 |
| A | HOH4099 |
| A | HOH4114 |
| site_id | BC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BRJ A 3804 |
| Chain | Residue |
| A | VAL106 |
| A | LEU110 |
| A | LEU216 |
| site_id | BC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE BRJ A 3805 |
| Chain | Residue |
| A | LYS98 |
| A | THR102 |
| A | LEU289 |
| A | GLY293 |
| A | LEU361 |
| site_id | BC6 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE BRJ A 3806 |
| Chain | Residue |
| A | ILE63 |
| A | ALA64 |
| A | TYR67 |
| A | ASN135 |
| A | ALA139 |
| C | ILE187 |
| C | GLN191 |
| site_id | BC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE BRJ C 3807 |
| Chain | Residue |
| C | GLU116 |
| C | ASN282 |
| C | GLN283 |
| C | THR286 |
| D | TYR119 |
| site_id | BC8 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BRJ C 3808 |
| Chain | Residue |
| C | TYR119 |
| D | GLU116 |
| D | THR286 |
| D | TYR287 |
| site_id | BC9 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE BRJ B 3809 |
| Chain | Residue |
| B | ILE63 |
| B | ALA64 |
| B | TYR67 |
| B | ASN135 |
| B | ALA139 |
| D | GLN191 |
| B | LEU62 |
| site_id | CC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BRJ C 3810 |
| Chain | Residue |
| C | GLN293 |
| C | HOH3816 |
| D | ARG122 |
| site_id | CC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BRJ C 3811 |
| Chain | Residue |
| C | ARG122 |
| C | GLY126 |
| D | ILE290 |
| D | GLN293 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000255 |
| Chain | Residue | Details |
| A | CYS151 | |
| B | CYS151 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU114 | |
| B | GLU209 | |
| B | GLU243 | |
| B | HIS246 | |
| A | GLU144 | |
| A | HIS147 | |
| A | GLU209 | |
| A | GLU243 | |
| A | HIS246 | |
| B | GLU114 | |
| B | GLU144 | |
| B | HIS147 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1mhy |
| Chain | Residue | Details |
| A | CYS151 | |
| A | THR213 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1mhy |
| Chain | Residue | Details |
| B | CYS151 | |
| B | THR213 |
