1XVB
soluble methane monooxygenase hydroxylase: 6-bromohexanol soaked structure
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0006730 | biological_process | one-carbon metabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0106317 | molecular_function | obsolete methane monooxygenase NADH activity |
| A | 0106318 | molecular_function | obsolete methane monooxygenase NADPH activity |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0006730 | biological_process | one-carbon metabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0106317 | molecular_function | obsolete methane monooxygenase NADH activity |
| B | 0106318 | molecular_function | obsolete methane monooxygenase NADPH activity |
| C | 0004497 | molecular_function | monooxygenase activity |
| C | 0005515 | molecular_function | protein binding |
| C | 0006730 | biological_process | one-carbon metabolic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| C | 0106317 | molecular_function | obsolete methane monooxygenase NADH activity |
| C | 0106318 | molecular_function | obsolete methane monooxygenase NADPH activity |
| D | 0004497 | molecular_function | monooxygenase activity |
| D | 0005515 | molecular_function | protein binding |
| D | 0006730 | biological_process | one-carbon metabolic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0016709 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen |
| D | 0106317 | molecular_function | obsolete methane monooxygenase NADH activity |
| D | 0106318 | molecular_function | obsolete methane monooxygenase NADPH activity |
| E | 0004497 | molecular_function | monooxygenase activity |
| E | 0006730 | biological_process | one-carbon metabolic process |
| E | 0015049 | molecular_function | methane monooxygenase [NAD(P)H] activity |
| E | 0015947 | biological_process | methane metabolic process |
| E | 0106317 | molecular_function | obsolete methane monooxygenase NADH activity |
| E | 0106318 | molecular_function | obsolete methane monooxygenase NADPH activity |
| F | 0004497 | molecular_function | monooxygenase activity |
| F | 0006730 | biological_process | one-carbon metabolic process |
| F | 0015049 | molecular_function | methane monooxygenase [NAD(P)H] activity |
| F | 0015947 | biological_process | methane metabolic process |
| F | 0106317 | molecular_function | obsolete methane monooxygenase NADH activity |
| F | 0106318 | molecular_function | obsolete methane monooxygenase NADPH activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FE A 1170 |
| Chain | Residue |
| A | GLU144 |
| A | GLU209 |
| A | GLU243 |
| A | HIS246 |
| A | FE1171 |
| A | BHL1203 |
| A | HOH1309 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FE A 1171 |
| Chain | Residue |
| A | HIS147 |
| A | FE1170 |
| A | BHL1203 |
| A | HOH1308 |
| A | HOH1309 |
| A | GLU114 |
| A | GLU144 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FE B 1172 |
| Chain | Residue |
| B | GLU144 |
| B | GLU209 |
| B | GLU243 |
| B | HIS246 |
| B | FE1173 |
| B | BHL1201 |
| B | HOH1295 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE FE B 1173 |
| Chain | Residue |
| B | GLU114 |
| B | GLU144 |
| B | HIS147 |
| B | FE1172 |
| B | BHL1201 |
| B | HOH1294 |
| B | HOH1295 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA C 1174 |
| Chain | Residue |
| C | GLU222 |
| C | HOH1296 |
| C | HOH1306 |
| C | HOH1374 |
| C | HOH1375 |
| C | HOH1456 |
| E | HOH193 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE BHL B 1201 |
| Chain | Residue |
| B | GLY113 |
| B | GLU114 |
| B | ALA117 |
| B | GLU144 |
| B | PHE188 |
| B | PHE192 |
| B | LEU204 |
| B | GLY208 |
| B | GLU209 |
| B | FE1172 |
| B | FE1173 |
| B | HOH1295 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE BHL B 1202 |
| Chain | Residue |
| B | LYS98 |
| B | GLU101 |
| B | THR102 |
| B | LEU180 |
| B | MET288 |
| B | GLY293 |
| B | PHE359 |
| B | LEU361 |
| B | HOH1314 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | BINDING SITE FOR RESIDUE BHL A 1203 |
| Chain | Residue |
| A | GLU114 |
| A | GLU144 |
| A | LEU204 |
| A | GLY208 |
| A | GLU209 |
| A | ILE217 |
| A | GLU243 |
| A | FE1170 |
| A | FE1171 |
| A | HOH1308 |
| A | HOH1309 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE BHL B 1205 |
| Chain | Residue |
| B | MET184 |
| B | PHE212 |
| B | LEU216 |
| B | GLN278 |
| B | TYR281 |
| B | PHE282 |
| site_id | BC1 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE BHL A 1206 |
| Chain | Residue |
| A | LYS98 |
| A | GLU101 |
| A | THR102 |
| A | LEU180 |
| A | LEU289 |
| A | GLY293 |
| A | PHE359 |
| A | LEU361 |
| A | HOH1361 |
| site_id | BC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE BHL A 1207 |
| Chain | Residue |
| A | VAL106 |
| A | PHE188 |
| A | LEU216 |
| A | TYR281 |
| A | PHE282 |
| A | LEU289 |
| A | HOH1449 |
| site_id | BC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE 3BR C 1208 |
| Chain | Residue |
| C | GLN293 |
| D | GLN125 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE BBU A 1209 |
| Chain | Residue |
| A | SER490 |
| A | ASP491 |
| C | LEU29 |
| C | ASP30 |
| site_id | BC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE BHL A 1200 |
| Chain | Residue |
| A | LEU405 |
| A | PHE519 |
| A | BHL1210 |
| site_id | BC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE BHL A 1210 |
| Chain | Residue |
| A | PHE408 |
| A | HIS413 |
| A | ILE415 |
| A | PHE519 |
| A | BHL1200 |
| A | LEU405 |
| site_id | BC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE BHL B 1211 |
| Chain | Residue |
| B | SER490 |
| B | ASP491 |
| B | GLY503 |
| B | LEU506 |
| D | LEU29 |
| D | HOH514 |
| site_id | BC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE BHL B 1212 |
| Chain | Residue |
| B | ILE409 |
| B | HIS413 |
| B | PRO414 |
| B | ILE415 |
| B | PHE519 |
| B | HOH1226 |
| site_id | BC9 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE 3BR C 1213 |
| Chain | Residue |
| C | ARG122 |
| C | GLN125 |
| D | GLN293 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | ACT_SITE: ACT_SITE => ECO:0000255 |
| Chain | Residue | Details |
| A | CYS151 | |
| B | CYS151 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU114 | |
| B | GLU209 | |
| B | GLU243 | |
| B | HIS246 | |
| A | GLU144 | |
| A | HIS147 | |
| A | GLU209 | |
| A | GLU243 | |
| A | HIS246 | |
| B | GLU114 | |
| B | GLU144 | |
| B | HIS147 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1mhy |
| Chain | Residue | Details |
| A | CYS151 | |
| A | THR213 |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1mhy |
| Chain | Residue | Details |
| B | CYS151 | |
| B | THR213 |
