1XUO
X-ray structure of LFA-1 I-domain bound to a 1,4-diazepane-2,5-dione inhibitor at 1.8A resolution
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG A 312 |
| Chain | Residue |
| A | SER139 |
| A | SER141 |
| A | ASP239 |
| A | GLU301 |
| A | HOH402 |
| A | HOH403 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MG B 312 |
| Chain | Residue |
| B | SER141 |
| B | ASP239 |
| B | HOH313 |
| A | HOH404 |
| A | HOH405 |
| B | SER139 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE LA1 A 401 |
| Chain | Residue |
| A | PHE153 |
| A | TYR166 |
| A | TYR257 |
| A | LEU302 |
| A | LYS305 |
| A | ILE306 |
| A | VAL308 |
| A | HOH486 |
| B | MET140 |
| B | LEU203 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19349973 |
| Chain | Residue | Details |
| A | ASN163 | |
| B | ASN163 |
