1XTK

structure of DECD to DEAD mutation of human UAP56

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000245	biological_process	spliceosomal complex assembly
A	0000346	cellular_component	transcription export complex
A	0000398	biological_process	mRNA splicing, via spliceosome
A	0003676	molecular_function	nucleic acid binding
A	0003689	molecular_function	DNA clamp loader activity
A	0003723	molecular_function	RNA binding
A	0003724	molecular_function	RNA helicase activity
A	0003729	molecular_function	mRNA binding
A	0004386	molecular_function	helicase activity
A	0005515	molecular_function	protein binding
A	0005524	molecular_function	ATP binding
A	0005634	cellular_component	nucleus
A	0005654	cellular_component	nucleoplasm
A	0005681	cellular_component	spliceosomal complex
A	0005687	cellular_component	U4 snRNP
A	0005688	cellular_component	U6 snRNP
A	0005737	cellular_component	cytoplasm
A	0006338	biological_process	chromatin remodeling
A	0006397	biological_process	mRNA processing
A	0006405	biological_process	RNA export from nucleus
A	0006406	biological_process	mRNA export from nucleus
A	0008186	molecular_function	ATP-dependent activity, acting on RNA
A	0008380	biological_process	RNA splicing
A	0010501	biological_process	RNA secondary structure unwinding
A	0016607	cellular_component	nuclear speck
A	0016787	molecular_function	hydrolase activity
A	0016887	molecular_function	ATP hydrolysis activity
A	0017070	molecular_function	U6 snRNA binding
A	0030621	molecular_function	U4 snRNA binding
A	0042802	molecular_function	identical protein binding
A	0043008	molecular_function	ATP-dependent protein binding
A	0051028	biological_process	mRNA transport
A	0061775	molecular_function	cohesin loader activity
A	0140584	molecular_function	chromatin extrusion motor activity
A	0140588	biological_process	chromatin looping
A	0140665	molecular_function	ATP-dependent H3-H4 histone complex chaperone activity
A	0140849	molecular_function	ATP-dependent H2AZ histone chaperone activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE BME A 916

Chain	Residue
A	ASP49

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Functional Information from PROSITE/UniProt

site_id	PS00039
Number of Residues	9
Details	DEAD_ATP_HELICASE DEAD-box subfamily ATP-dependent helicases signature. ILDEADKmL

Chain	Residue	Details
A	ILE194-LEU202

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	BINDING:

Chain	Residue	Details
A	ALA89

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site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	THR172

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