1XTK
structure of DECD to DEAD mutation of human UAP56
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000245 | biological_process | spliceosomal complex assembly |
| A | 0000346 | cellular_component | transcription export complex |
| A | 0000398 | biological_process | mRNA splicing, via spliceosome |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0003723 | molecular_function | RNA binding |
| A | 0003724 | molecular_function | RNA helicase activity |
| A | 0003729 | molecular_function | mRNA binding |
| A | 0004386 | molecular_function | helicase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005681 | cellular_component | spliceosomal complex |
| A | 0005687 | cellular_component | U4 snRNP |
| A | 0005688 | cellular_component | U6 snRNP |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006397 | biological_process | mRNA processing |
| A | 0006405 | biological_process | RNA export from nucleus |
| A | 0006406 | biological_process | mRNA export from nucleus |
| A | 0008186 | molecular_function | ATP-dependent activity, acting on RNA |
| A | 0008380 | biological_process | RNA splicing |
| A | 0016607 | cellular_component | nuclear speck |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0016887 | molecular_function | ATP hydrolysis activity |
| A | 0017070 | molecular_function | U6 snRNA binding |
| A | 0030621 | molecular_function | U4 snRNA binding |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0043008 | molecular_function | ATP-dependent protein binding |
| A | 0051028 | biological_process | mRNA transport |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE BME A 916 |
| Chain | Residue |
| A | ASP49 |
Functional Information from PROSITE/UniProt
| site_id | PS00039 |
| Number of Residues | 9 |
| Details | DEAD_ATP_HELICASE DEAD-box subfamily ATP-dependent helicases signature. ILDEADKmL |
| Chain | Residue | Details |
| A | ILE194-LEU202 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 173 |
| Details | Domain: {"description":"Helicase ATP-binding","evidences":[{"source":"PROSITE-ProRule","id":"PRU00541","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 161 |
| Details | Domain: {"description":"Helicase C-terminal","evidences":[{"source":"PROSITE-ProRule","id":"PRU00542","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Motif: {"description":"DECD box"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 7 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"20068231","evidenceCode":"ECO:0007744"},{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
