Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1XSI

Structure of a Family 31 alpha glycosidase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
A	0005975	biological_process	carbohydrate metabolic process
A	0016787	molecular_function	hydrolase activity
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0030246	molecular_function	carbohydrate binding
A	0042802	molecular_function	identical protein binding
A	0061634	molecular_function	alpha-D-xyloside xylohydrolase
A	0080176	molecular_function	xyloglucan 1,6-alpha-xylosidase activity
B	0003824	molecular_function	catalytic activity
B	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
B	0005975	biological_process	carbohydrate metabolic process
B	0016787	molecular_function	hydrolase activity
B	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
B	0030246	molecular_function	carbohydrate binding
B	0042802	molecular_function	identical protein binding
B	0061634	molecular_function	alpha-D-xyloside xylohydrolase
B	0080176	molecular_function	xyloglucan 1,6-alpha-xylosidase activity
C	0003824	molecular_function	catalytic activity
C	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
C	0005975	biological_process	carbohydrate metabolic process
C	0016787	molecular_function	hydrolase activity
C	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
C	0030246	molecular_function	carbohydrate binding
C	0042802	molecular_function	identical protein binding
C	0061634	molecular_function	alpha-D-xyloside xylohydrolase
C	0080176	molecular_function	xyloglucan 1,6-alpha-xylosidase activity
D	0003824	molecular_function	catalytic activity
D	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
D	0005975	biological_process	carbohydrate metabolic process
D	0016787	molecular_function	hydrolase activity
D	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
D	0030246	molecular_function	carbohydrate binding
D	0042802	molecular_function	identical protein binding
D	0061634	molecular_function	alpha-D-xyloside xylohydrolase
D	0080176	molecular_function	xyloglucan 1,6-alpha-xylosidase activity
E	0003824	molecular_function	catalytic activity
E	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
E	0005975	biological_process	carbohydrate metabolic process
E	0016787	molecular_function	hydrolase activity
E	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
E	0030246	molecular_function	carbohydrate binding
E	0042802	molecular_function	identical protein binding
E	0061634	molecular_function	alpha-D-xyloside xylohydrolase
E	0080176	molecular_function	xyloglucan 1,6-alpha-xylosidase activity
F	0003824	molecular_function	catalytic activity
F	0004553	molecular_function	hydrolase activity, hydrolyzing O-glycosyl compounds
F	0005975	biological_process	carbohydrate metabolic process
F	0016787	molecular_function	hydrolase activity
F	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
F	0030246	molecular_function	carbohydrate binding
F	0042802	molecular_function	identical protein binding
F	0061634	molecular_function	alpha-D-xyloside xylohydrolase
F	0080176	molecular_function	xyloglucan 1,6-alpha-xylosidase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 F 3001

Chain	Residue
F	VAL626
F	GLN627

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 F 3002

Chain	Residue
F	ARG568
F	ALA687
F	HIS689
F	GLN757

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 F 3003

Chain	Residue
F	THR246
F	LYS248
F	ARG583

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 D 3004

Chain	Residue
D	THR246
D	ARG583
D	HOH3068

site_id	AC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 F 3005

Chain	Residue
A	LYS403
F	TYR680
F	VAL681

site_id	AC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 E 3006

Chain	Residue
E	THR246
E	ARG583
E	HOH3083

site_id	AC7
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 C 3007

Chain	Residue
C	THR246
C	ARG583
C	HOH3142

site_id	AC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 B 3008

Chain	Residue
B	THR246
B	LYS248
B	ALA249
B	ARG583

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 F 3009

Chain	Residue
F	ARG333
F	ARG334

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 3010

Chain	Residue
B	ARG568
B	HIS689
B	GLN757

site_id	BC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 D 3011

Chain	Residue
D	ASN145
D	ARG147

site_id	BC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 C 3012

Chain	Residue
C	GLU24
C	VAL25
C	ASN96
C	LYS114

site_id	BC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 3013

Chain	Residue
B	ASN145
B	ARG147

site_id	BC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 3014

Chain	Residue
A	ARG147
A	GLN434

site_id	BC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 3015

Chain	Residue
B	ARG648
C	ARG648

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 B 3016

Chain	Residue
B	VAL626
B	GLN627

site_id	BC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 A 3017

Chain	Residue
A	THR246
A	LYS248
A	ARG583

site_id	BC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 A 3018

Chain	Residue
A	ASN145
A	ARG147

site_id	CC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MPO B 1001

Chain	Residue
B	HIS640
B	ASP642
B	HIS654
B	GLY655
B	SER658

site_id	CC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MPO C 1002

Chain	Residue
C	HIS640
C	ASP642
C	GLN652
C	GLN653
C	HIS654
C	GLY655

site_id	CC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE MPO D 1003

Chain	Residue
D	HIS640
D	ASP642
D	GLN652
D	GLN653
D	HIS654
D	GLY655
D	SER658
D	HOH3145
D	HOH3168

site_id	CC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE MPO E 1004

Chain	Residue
E	HIS640
E	ASP642
E	GLN652
E	GLN653
E	HIS654
E	GLY655
E	SER658

site_id	CC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACY E 2001

Chain	Residue
E	ASP306
E	LYS414
E	ASP416
E	ASP482
E	PHE515
E	HIS540

site_id	CC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE ACY F 2002

Chain	Residue
F	ASP306
F	LYS414
F	ASP416
F	ASP482
F	PHE515
F	HIS540

site_id	CC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ACY A 2003

Chain	Residue
A	PHE277
A	ASP306
A	LYS414
A	ASP416
A	ASP482
A	PHE515
A	HIS540

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	6
Details	Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"15501829","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	6
Details	Active site: {"evidences":[{"source":"PubMed","id":"15501829","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	6
Details	Active site: {"description":"Proton donor","evidences":[{"source":"PubMed","id":"15501829","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)