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1XP6

HUMAN ESTROGEN RECEPTOR ALPHA LIGAND-BINDING DOMAIN IN COMPLEX WITH COMPOUND 16

Functional Information from PDB Data
site_idAC1
Number of Residues15
DetailsBINDING SITE FOR RESIDUE AIU A 600
ChainResidue
ALEU346
APHE404
AGLY521
AHIS524
ALYS531
ALEU539
AHOH1008
ATHR347
AALA350
AASP351
AGLU353
ALEU354
ATRP383
ALEU387
AARG394

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues3
DetailsBINDING: BINDING => ECO:0000269|PubMed:9338790, ECO:0000269|PubMed:9600906, ECO:0007744|PDB:1A52, ECO:0007744|PDB:1ERE
ChainResidueDetails
AGLU353
AARG394
AHIS524

site_idSWS_FT_FI2
Number of Residues1
DetailsMOD_RES: Phosphotyrosine; by Tyr-kinases => ECO:0000269|PubMed:7539106
ChainResidueDetails
ATYR537

site_idSWS_FT_FI3
Number of Residues1
DetailsLIPID: S-palmitoyl cysteine => ECO:0000250
ChainResidueDetails
ACYS447

227111

PDB entries from 2024-11-06

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