1XMH

Structure of Co(II) reconstituted methane monooxygenase hydroxylase from M. capsulatus (Bath)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004497	molecular_function	monooxygenase activity
A	0005515	molecular_function	protein binding
A	0006730	biological_process	one-carbon metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
A	0106317	molecular_function	obsolete methane monooxygenase NADH activity
A	0106318	molecular_function	obsolete methane monooxygenase NADPH activity
B	0004497	molecular_function	monooxygenase activity
B	0005515	molecular_function	protein binding
B	0006730	biological_process	one-carbon metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
B	0106317	molecular_function	obsolete methane monooxygenase NADH activity
B	0106318	molecular_function	obsolete methane monooxygenase NADPH activity
C	0004497	molecular_function	monooxygenase activity
C	0005515	molecular_function	protein binding
C	0006730	biological_process	one-carbon metabolic process
C	0016491	molecular_function	oxidoreductase activity
C	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
C	0106317	molecular_function	obsolete methane monooxygenase NADH activity
C	0106318	molecular_function	obsolete methane monooxygenase NADPH activity
D	0004497	molecular_function	monooxygenase activity
D	0005515	molecular_function	protein binding
D	0006730	biological_process	one-carbon metabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0016709	molecular_function	oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen, NAD(P)H as one donor, and incorporation of one atom of oxygen
D	0106317	molecular_function	obsolete methane monooxygenase NADH activity
D	0106318	molecular_function	obsolete methane monooxygenase NADPH activity
E	0004497	molecular_function	monooxygenase activity
E	0006730	biological_process	one-carbon metabolic process
E	0015049	molecular_function	methane monooxygenase [NAD(P)H] activity
E	0015947	biological_process	methane metabolic process
E	0106317	molecular_function	obsolete methane monooxygenase NADH activity
E	0106318	molecular_function	obsolete methane monooxygenase NADPH activity
F	0004497	molecular_function	monooxygenase activity
F	0006730	biological_process	one-carbon metabolic process
F	0015049	molecular_function	methane monooxygenase [NAD(P)H] activity
F	0015947	biological_process	methane metabolic process
F	0106317	molecular_function	obsolete methane monooxygenase NADH activity
F	0106318	molecular_function	obsolete methane monooxygenase NADPH activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CO A 5170

Chain	Residue
A	GLN140
A	GLU144
A	GLU209
A	GLU243
A	HIS246
A	CO5171
A	HOH5322

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CO A 5171

Chain	Residue
A	HIS147
A	GLU243
A	CO5170
A	HOH5322
A	HOH5323
A	GLU114
A	GLU144

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site_id	AC3
Number of Residues	7
Details	BINDING SITE FOR RESIDUE CO B 5172

Chain	Residue
B	GLU114
B	GLU144
B	HIS147
B	GLU243
B	CO5173
B	HOH5307
B	HOH5308

---

site_id	AC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CO B 5173

Chain	Residue
B	GLU144
B	GLU209
B	GLU243
B	HIS246
B	CO5172
B	HOH5308

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: ACT_SITE => ECO:0000255

Chain	Residue	Details
A	CYS151
B	CYS151

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site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING:

Chain	Residue	Details
A	GLU114
B	GLU209
B	GLU243
B	HIS246
A	GLU144
A	HIS147
A	GLU209
A	GLU243
A	HIS246
B	GLU114
B	GLU144
B	HIS147

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 1mhy

Chain	Residue	Details
A	CYS151
A	THR213

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site_id	CSA2
Number of Residues	2
Details	Annotated By Reference To The Literature 1mhy

Chain	Residue	Details
B	CYS151
B	THR213

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