Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004450 | molecular_function | isocitrate dehydrogenase (NADP+) activity |
| A | 0006097 | biological_process | glyoxylate cycle |
| A | 0006099 | biological_process | tricarboxylic acid cycle |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004450 | molecular_function | isocitrate dehydrogenase (NADP+) activity |
| B | 0006097 | biological_process | glyoxylate cycle |
| B | 0006099 | biological_process | tricarboxylic acid cycle |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016616 | molecular_function | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE CA A 1005 |
| Chain | Residue |
| A | ASP287 |
| B | ASP311 |
| B | ICT1004 |
| B | HOH1005 |
| B | HOH1006 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE CA A 1006 |
| Chain | Residue |
| A | HOH1136 |
| A | HOH1137 |
| B | ASP287 |
| A | ASP311 |
| A | ASP315 |
| A | ICT1002 |
| A | HOH1135 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE NAP A 1001 |
| Chain | Residue |
| A | LYS107 |
| A | PRO109 |
| A | LEU110 |
| A | THR112 |
| A | ASN122 |
| A | GLY325 |
| A | GLU340 |
| A | PRO341 |
| A | VAL342 |
| A | HIS343 |
| A | GLY344 |
| A | THR345 |
| A | ALA346 |
| A | TYR349 |
| A | ILE355 |
| A | ASN356 |
| A | ASP397 |
| A | ARG400 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ICT A 1002 |
| Chain | Residue |
| A | ARG136 |
| A | ARG159 |
| A | TYR166 |
| A | ASP311 |
| A | CA1006 |
| A | HOH1136 |
| B | LYS233 |
| B | ASN235 |
| B | ASP287 |
| site_id | AC5 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE NAP B 1003 |
| Chain | Residue |
| A | ASN235 |
| A | ILE285 |
| A | ASN288 |
| A | GLN291 |
| A | GLN292 |
| A | ARG296 |
| B | PRO109 |
| B | LEU110 |
| B | THR112 |
| B | ASN122 |
| B | ARG126 |
| B | ILE324 |
| B | GLY325 |
| B | GLU340 |
| B | VAL342 |
| B | HIS343 |
| B | GLY344 |
| B | THR345 |
| B | ALA346 |
| B | LYS348 |
| B | TYR349 |
| B | ILE355 |
| B | ASN356 |
| B | ASP397 |
| B | ICT1004 |
| B | HOH1008 |
| B | HOH1009 |
| B | HOH1010 |
| site_id | AC6 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE ICT B 1004 |
| Chain | Residue |
| A | LYS233 |
| A | ASP287 |
| A | CA1005 |
| B | THR112 |
| B | SER120 |
| B | ASN122 |
| B | ARG126 |
| B | ARG136 |
| B | ARG159 |
| B | TYR166 |
| B | ASP311 |
| B | NAP1003 |
| B | HOH1005 |
| B | HOH1007 |
Functional Information from PROSITE/UniProt
| site_id | PS00470 |
| Number of Residues | 20 |
| Details | IDH_IMDH Isocitrate and isopropylmalate dehydrogenases signature. NLNGDYiSDaaSalv.GGIGM |
| Chain | Residue | Details |
| A | ASN307-MET326 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a05 |
| Chain | Residue | Details |
| A | ASP287 | |
| A | LYS233 | |
| B | TYR166 | |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1a05 |
| Chain | Residue | Details |
| A | TYR166 | |
| B | ASP287 | |
| B | LYS233 | |
