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1XK9

Pseudomanas exotoxin A in complex with the PJ34 inhibitor

Functional Information from GO Data
ChainGOidnamespacecontents
A0047286molecular_functionNAD+-diphthamide ADP-ribosyltransferase activity
B0047286molecular_functionNAD+-diphthamide ADP-ribosyltransferase activity
Functional Information from PDB Data
site_idAC1
Number of Residues8
DetailsBINDING SITE FOR RESIDUE P34 A 1001
ChainResidue
AHIS440
AGLY441
ATYR470
AILE471
AALA478
ATYR481
AGLN485
AHOH1051

site_idAC2
Number of Residues8
DetailsBINDING SITE FOR RESIDUE P34 B 2001
ChainResidue
BGLY441
BTYR470
BILE471
BTYR481
BGLN485
BGLU553
BHOH2098
BHIS440

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsACT_SITE: ACT_SITE => ECO:0000269|PubMed:2885323
ChainResidueDetails
AGLU553
BGLU553

site_idSWS_FT_FI2
Number of Residues8
DetailsBINDING: BINDING => ECO:0000269|PubMed:18583986
ChainResidueDetails
AHIS440
ASER449
AGLY454
AGLU553
BHIS440
BSER449
BGLY454
BGLU553

Catalytic Information from CSA
site_idCSA1
Number of Residues1
DetailsAnnotated By Reference To The Literature 1zm2
ChainResidueDetails
AGLU553

site_idCSA2
Number of Residues1
DetailsAnnotated By Reference To The Literature 1zm2
ChainResidueDetails
BGLU553

site_idMCSA1
Number of Residues1
DetailsM-CSA 769
ChainResidueDetails
AGLU553electrostatic stabiliser

site_idMCSA2
Number of Residues1
DetailsM-CSA 769
ChainResidueDetails
BGLU553electrostatic stabiliser

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PDB entries from 2024-10-30

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