1XJT

Crystal structure of active form of P1 phage endolysin Lyz

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003796	molecular_function	lysozyme activity
A	0009253	biological_process	peptidoglycan catabolic process
A	0016020	cellular_component	membrane
A	0016798	molecular_function	hydrolase activity, acting on glycosyl bonds
A	0016998	biological_process	cell wall macromolecule catabolic process
A	0020002	cellular_component	host cell plasma membrane
A	0031640	biological_process	killing of cells of another organism
A	0042742	biological_process	defense response to bacterium

Functional Information from PDB Data

site_id	AC1
Number of Residues	10
Details	BINDING SITE FOR RESIDUE CIT A 192

Chain	Residue
A	ILE21
A	HOH386
A	GLN94
A	HIS95
A	ARG122
A	HIS138
A	GLN142
A	HOH334
A	HOH378
A	HOH379

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site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CIT A 250

Chain	Residue
A	TYR124
A	THR135
A	SER136
A	ASP155
A	HOH285
A	HOH354

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	5
Details	TOPO_DOM: Cytoplasmic => ECO:0000305

Chain	Residue	Details
A	MET1-ALA6

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site_id	SWS_FT_FI2
Number of Residues	17
Details	TRANSMEM: Helical; Signal-anchor for type II membrane protein => ECO:0000255

Chain	Residue	Details
A	ALA7-GLY24

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site_id	SWS_FT_FI3
Number of Residues	160
Details	TOPO_DOM: Periplasmic => ECO:0000269|PubMed:15090650

Chain	Residue	Details
A	ASN25-GLU185

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site_id	SWS_FT_FI4
Number of Residues	1
Details	ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04136, ECO:0000305|PubMed:15637279

Chain	Residue	Details
A	GLU42

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site_id	SWS_FT_FI5
Number of Residues	1
Details	ACT_SITE: Proton donor/acceptor => ECO:0000255|HAMAP-Rule:MF_04136, ECO:0000269|PubMed:15637279

Chain	Residue	Details
A	CYS51

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	2
Details	Annotated By Reference To The Literature 206l

Chain	Residue	Details
A	GLU42
A	CYS51

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