1XJF
Structural mechanism of allosteric substrate specificity in a ribonucleotide reductase: dATP complex
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004748 | molecular_function | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
| A | 0005524 | molecular_function | ATP binding |
| A | 0009263 | biological_process | deoxyribonucleotide biosynthetic process |
| A | 0031419 | molecular_function | cobalamin binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004748 | molecular_function | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
| B | 0005524 | molecular_function | ATP binding |
| B | 0009263 | biological_process | deoxyribonucleotide biosynthetic process |
| B | 0031419 | molecular_function | cobalamin binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE MG B 1003 |
| Chain | Residue |
| B | DTP1001 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE MG A 1004 |
| Chain | Residue |
| A | DTP1002 |
| site_id | AC3 |
| Number of Residues | 18 |
| Details | BINDING SITE FOR RESIDUE DTP B 1001 |
| Chain | Residue |
| B | ARG171 |
| B | VAL177 |
| B | ALA178 |
| B | GLY179 |
| B | THR180 |
| B | LYS183 |
| B | ALA184 |
| B | SER185 |
| B | PHE190 |
| B | MG1003 |
| B | HOH1005 |
| A | LYS158 |
| A | VAL200 |
| A | LYS202 |
| B | ASP141 |
| B | SER142 |
| B | ILE143 |
| B | ILE146 |
| site_id | AC4 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE DTP A 1002 |
| Chain | Residue |
| A | ASP141 |
| A | SER142 |
| A | ILE143 |
| A | ILE146 |
| A | ARG171 |
| A | VAL177 |
| A | ALA178 |
| A | GLY179 |
| A | THR180 |
| A | LYS183 |
| A | ALA184 |
| A | SER185 |
| A | PHE190 |
| A | MG1004 |
| A | HOH1026 |
| B | LYS158 |
| B | VAL200 |
| B | VAL201 |
| B | LYS202 |
