1XIU
Crystal structure of the agonist-bound ligand-binding domain of Biomphalaria glabrata RXR
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003707 | molecular_function | nuclear steroid receptor activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0008270 | molecular_function | zinc ion binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003707 | molecular_function | nuclear steroid receptor activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0008270 | molecular_function | zinc ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 9CR A 201 |
| Chain | Residue |
| A | ALA245 |
| A | HIS409 |
| A | ALA246 |
| A | GLN249 |
| A | PHE287 |
| A | ARG290 |
| A | LEU300 |
| A | ALA301 |
| A | VAL316 |
| A | CYS406 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE 9CR B 202 |
| Chain | Residue |
| B | ILE242 |
| B | ALA246 |
| B | GLN249 |
| B | PHE287 |
| B | ARG290 |
| B | LEU300 |
| B | ALA301 |
| B | CYS406 |
| B | HIS409 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"16274693","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1XIU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 223 |
| Details | Domain: {"description":"NR LBD","evidences":[{"source":"PROSITE-ProRule","id":"PRU01189","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"16274693","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 8 |
| Details | Motif: {"description":"LXXLL motif 4"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"23186163","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
