Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0005515 | molecular_function | protein binding |
A | 0005737 | cellular_component | cytoplasm |
A | 0005829 | cellular_component | cytosol |
A | 0008047 | molecular_function | enzyme activator activity |
A | 0016671 | molecular_function | oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor |
A | 0043085 | biological_process | positive regulation of catalytic activity |
Functional Information from PROSITE/UniProt
site_id | PS00194 |
Number of Residues | 19 |
Details | THIOREDOXIN_1 Thioredoxin family active site. VVdFTasWCGPCRfIapfF |
Chain | Residue | Details |
A | VAL32-PHE50 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Nucleophile => ECO:0000250 |
Chain | Residue | Details |
A | CYS40 | |
A | CYS43 | |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | SITE: Deprotonates C-terminal active site Cys => ECO:0000250 |
Chain | Residue | Details |
A | ASP34 | |
site_id | SWS_FT_FI3 |
Number of Residues | 2 |
Details | SITE: Contributes to redox potential value => ECO:0000250 |
Chain | Residue | Details |
A | GLY41 | |
A | PRO42 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1mek |
Chain | Residue | Details |
A | PRO42 | |
A | CYS40 | |
A | CYS43 | |
A | GLY41 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1mek |
Chain | Residue | Details |
A | CYS40 | |
A | CYS43 | |