1XDN

High resolution crystal structure of an editosome enzyme from trypanosoma brucei: RNA editing ligase 1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003972	molecular_function	RNA ligase (ATP) activity
A	0005524	molecular_function	ATP binding
A	0016874	molecular_function	ligase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG A 502

Chain	Residue
A	ATP501
A	HOH514
A	HOH520
A	HOH528
A	HOH530

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site_id	AC2
Number of Residues	27
Details	BINDING SITE FOR RESIDUE ATP A 501

Chain	Residue
A	GLU86
A	LYS87
A	VAL88
A	ASN92
A	ARG111
A	GLU159
A	PHE209
A	VAL286
A	LYS307
A	ARG309
A	MG502
A	HOH514
A	HOH520
A	HOH528
A	HOH530
A	HOH536
A	HOH587
A	HOH634
A	HOH650
A	HOH777
A	HOH829
A	HOH871
A	HOH886
A	TYR58
A	ILE59
A	GLU60
A	ILE61

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: N6-AMP-lysine intermediate => ECO:0000305|PubMed:15465048

Chain	Residue	Details
A	LYS87

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site_id	SWS_FT_FI2
Number of Residues	7
Details	BINDING: BINDING => ECO:0000269|PubMed:15465048, ECO:0007744|PDB:1XDN

Chain	Residue	Details
A	ILE59
A	GLU86
A	ASN92
A	ARG111
A	GLU159
A	PHE209
A	LYS307

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