1XCL
Guanidinoacetate methyltransferase containing S-adenosylhomocysteine and guanidine
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006601 | biological_process | creatine biosynthetic process |
| A | 0007283 | biological_process | spermatogenesis |
| A | 0008168 | molecular_function | methyltransferase activity |
| A | 0008757 | molecular_function | S-adenosylmethionine-dependent methyltransferase activity |
| A | 0009887 | biological_process | animal organ morphogenesis |
| A | 0016740 | molecular_function | transferase activity |
| A | 0030731 | molecular_function | guanidinoacetate N-methyltransferase activity |
| A | 0032259 | biological_process | methylation |
| A | 0040014 | biological_process | regulation of multicellular organism growth |
| A | 0042802 | molecular_function | identical protein binding |
| A | 0046498 | biological_process | S-adenosylhomocysteine metabolic process |
| A | 0046500 | biological_process | S-adenosylmethionine metabolic process |
| A | 1990402 | biological_process | embryonic liver development |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE SAH A 236 |
| Chain | Residue |
| A | TRP19 |
| A | ILE72 |
| A | ALA73 |
| A | GLU89 |
| A | CYS90 |
| A | ASN91 |
| A | VAL94 |
| A | GLY114 |
| A | LEU115 |
| A | TRP116 |
| A | GLU117 |
| A | VAL40 |
| A | ASP134 |
| A | THR135 |
| A | TYR136 |
| A | LEU138 |
| A | GAI237 |
| A | HOH1003 |
| A | MET41 |
| A | MET49 |
| A | GLY67 |
| A | PHE68 |
| A | GLY69 |
| A | MET70 |
| A | ALA71 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GAI A 237 |
| Chain | Residue |
| A | VAL40 |
| A | MET41 |
| A | GLU45 |
| A | ASP134 |
| A | THR135 |
| A | SAH236 |
| A | HOH1011 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 223 |
| Details | Domain: {"description":"RMT2","evidences":[{"source":"PROSITE-ProRule","id":"PRU00892","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 11 |
| Details | Binding site: {} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00892","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15533043","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1XCJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15533043","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1XCJ","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
