Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1X9F

Hemoglobin Dodecamer from Lumbricus Erythrocruorin

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005344	molecular_function	oxygen carrier activity
A	0005506	molecular_function	iron ion binding
A	0005576	cellular_component	extracellular region
A	0005833	cellular_component	hemoglobin complex
A	0015671	biological_process	oxygen transport
A	0019825	molecular_function	oxygen binding
A	0020037	molecular_function	heme binding
A	0046872	molecular_function	metal ion binding
B	0005344	molecular_function	oxygen carrier activity
B	0005506	molecular_function	iron ion binding
B	0005576	cellular_component	extracellular region
B	0005833	cellular_component	hemoglobin complex
B	0015671	biological_process	oxygen transport
B	0019825	molecular_function	oxygen binding
B	0020037	molecular_function	heme binding
B	0046872	molecular_function	metal ion binding
C	0005344	molecular_function	oxygen carrier activity
C	0005506	molecular_function	iron ion binding
C	0005576	cellular_component	extracellular region
C	0005833	cellular_component	hemoglobin complex
C	0015671	biological_process	oxygen transport
C	0019825	molecular_function	oxygen binding
C	0020037	molecular_function	heme binding
C	0046872	molecular_function	metal ion binding
D	0005344	molecular_function	oxygen carrier activity
D	0005506	molecular_function	iron ion binding
D	0005576	cellular_component	extracellular region
D	0005833	cellular_component	hemoglobin complex
D	0015671	biological_process	oxygen transport
D	0019825	molecular_function	oxygen binding
D	0020037	molecular_function	heme binding
D	0046872	molecular_function	metal ion binding
E	0005344	molecular_function	oxygen carrier activity
E	0005506	molecular_function	iron ion binding
E	0005576	cellular_component	extracellular region
E	0005833	cellular_component	hemoglobin complex
E	0015671	biological_process	oxygen transport
E	0019825	molecular_function	oxygen binding
E	0020037	molecular_function	heme binding
E	0046872	molecular_function	metal ion binding
F	0005344	molecular_function	oxygen carrier activity
F	0005506	molecular_function	iron ion binding
F	0005576	cellular_component	extracellular region
F	0005833	cellular_component	hemoglobin complex
F	0015671	biological_process	oxygen transport
F	0019825	molecular_function	oxygen binding
F	0020037	molecular_function	heme binding
F	0046872	molecular_function	metal ion binding
G	0005344	molecular_function	oxygen carrier activity
G	0005506	molecular_function	iron ion binding
G	0005576	cellular_component	extracellular region
G	0005833	cellular_component	hemoglobin complex
G	0015671	biological_process	oxygen transport
G	0019825	molecular_function	oxygen binding
G	0020037	molecular_function	heme binding
G	0046872	molecular_function	metal ion binding
H	0005344	molecular_function	oxygen carrier activity
H	0005506	molecular_function	iron ion binding
H	0005576	cellular_component	extracellular region
H	0005833	cellular_component	hemoglobin complex
H	0015671	biological_process	oxygen transport
H	0019825	molecular_function	oxygen binding
H	0020037	molecular_function	heme binding
H	0046872	molecular_function	metal ion binding
I	0005344	molecular_function	oxygen carrier activity
I	0005506	molecular_function	iron ion binding
I	0005576	cellular_component	extracellular region
I	0005833	cellular_component	hemoglobin complex
I	0015671	biological_process	oxygen transport
I	0019825	molecular_function	oxygen binding
I	0020037	molecular_function	heme binding
I	0046872	molecular_function	metal ion binding
J	0005344	molecular_function	oxygen carrier activity
J	0005506	molecular_function	iron ion binding
J	0005576	cellular_component	extracellular region
J	0005833	cellular_component	hemoglobin complex
J	0015671	biological_process	oxygen transport
J	0019825	molecular_function	oxygen binding
J	0020037	molecular_function	heme binding
J	0046872	molecular_function	metal ion binding
K	0005344	molecular_function	oxygen carrier activity
K	0005506	molecular_function	iron ion binding
K	0005576	cellular_component	extracellular region
K	0005833	cellular_component	hemoglobin complex
K	0015671	biological_process	oxygen transport
K	0019825	molecular_function	oxygen binding
K	0020037	molecular_function	heme binding
K	0046872	molecular_function	metal ion binding
L	0005344	molecular_function	oxygen carrier activity
L	0005506	molecular_function	iron ion binding
L	0005576	cellular_component	extracellular region
L	0005833	cellular_component	hemoglobin complex
L	0015671	biological_process	oxygen transport
L	0019825	molecular_function	oxygen binding
L	0020037	molecular_function	heme binding
L	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 G 154

Chain	Residue
F	ARG50
G	ASP96
G	HIS97
G	HIS100

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE PO4 K 154

Chain	Residue
J	ARG50
K	ASP96
K	HIS97
K	HIS100

site_id	AC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE PO4 C 154

Chain	Residue
C	HIS97
C	HIS100
B	ARG50

site_id	AC4
Number of Residues	14
Details	BINDING SITE FOR RESIDUE HEM A 160

Chain	Residue
A	LEU52
A	PHE53
A	ARG55
A	VAL56
A	ARG72
A	HIS101
A	ARG104
A	TYR111
A	PHE112
A	PHE139
A	CMO1161
A	HOH1162
D	HIS89
D	GLN93

site_id	AC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CMO A 1161

Chain	Residue
A	PHE39
A	PHE53
A	HIS69
A	VAL73
A	HEM160

site_id	AC6
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEM B 160

Chain	Residue
B	LEU47
B	PHE48
B	ARG50
B	ARG67
B	LEU92
B	GLN95
B	HIS96
B	ARG99
B	ILE101
B	PHE109
B	GLU138
B	CMO1162
B	HOH1191
C	HIS97
C	GLN101

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CMO B 1162

Chain	Residue
B	TRP34
B	PHE48
B	HIS64
B	VAL68
B	HEM160

site_id	AC8
Number of Residues	22
Details	BINDING SITE FOR RESIDUE HEM C 160

Chain	Residue
B	HIS91
B	GLN95
C	LEU53
C	PHE54
C	ARG56
C	VAL57
C	ARG73
C	ILE74
C	GLY77
C	LEU78
C	LEU98
C	GLN101
C	HIS102
C	ARG105
C	VAL108
C	HIS112
C	PHE113
C	PHE116
C	LEU144
C	CMO1163
C	HOH1171
C	HOH1178

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CMO C 1163

Chain	Residue
C	LEU40
C	HIS70
C	ILE74
C	HEM160

site_id	BC1
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM D 160

Chain	Residue
A	HIS96
A	GLN100
D	PRO45
D	PHE46
D	ARG48
D	VAL49
D	HIS62
D	ARG65
D	LEU90
D	GLN93
D	HIS94
D	ARG97
D	LEU99
D	PHE103
D	PHE104
D	PHE107
D	ILE136
D	CMO1164
D	HOH1170
D	HOH1177

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CMO D 1164

Chain	Residue
D	VAL66
D	HEM160
D	TRP32
D	PHE46
D	HIS62

site_id	BC3
Number of Residues	14
Details	BINDING SITE FOR RESIDUE HEM E 160

Chain	Residue
E	LEU52
E	PHE53
E	ARG55
E	VAL56
E	ARG72
E	HIS101
E	ARG104
E	TYR111
E	PHE112
E	PHE139
E	CMO2161
E	HOH2166
H	HIS89
H	GLN93

site_id	BC4
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CMO E 2161

Chain	Residue
E	PHE39
E	PHE53
E	HIS69
E	VAL73
E	HEM160

site_id	BC5
Number of Residues	17
Details	BINDING SITE FOR RESIDUE HEM F 160

Chain	Residue
F	LEU47
F	PHE48
F	ARG50
F	ARG67
F	LEU72
F	GLN95
F	HIS96
F	ARG99
F	ILE101
F	PHE106
F	PHE109
F	GLU138
F	ILE141
F	CMO2162
F	HOH2164
G	HIS97
G	GLN101

site_id	BC6
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CMO F 2162

Chain	Residue
F	TRP34
F	PHE48
F	HIS64
F	VAL68
F	HEM160

site_id	BC7
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM G 160

Chain	Residue
F	HIS91
F	GLN95
G	LEU53
G	PHE54
G	ARG56
G	VAL57
G	ARG73
G	GLY77
G	LEU78
G	LEU98
G	GLN101
G	HIS102
G	ARG105
G	VAL108
G	HIS112
G	PHE113
G	PHE116
G	LEU144
G	CMO2163
G	HOH2168

site_id	BC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CMO G 2163

Chain	Residue
G	LEU40
G	PHE54
G	HIS70
G	ILE74
G	HEM160

site_id	BC9
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM H 160

Chain	Residue
A	HOH1170
E	HIS96
E	GLN100
H	PRO45
H	PHE46
H	ARG48
H	VAL49
H	HIS62
H	ARG65
H	LEU70
H	LEU90
H	GLN93
H	HIS94
H	ARG97
H	LEU99
H	PHE103
H	PHE104
H	PHE107
H	ILE136
H	CMO2164

site_id	CC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CMO H 2164

Chain	Residue
H	TRP32
H	PHE46
H	HIS62
H	VAL66
H	HEM160

site_id	CC2
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEM I 160

Chain	Residue
I	LEU52
I	PHE53
I	ARG55
I	VAL56
I	ARG72
I	HIS101
I	ARG104
I	TYR111
I	PHE112
I	PHE139
I	CMO3161
I	HOH3179
I	HOH3192
L	HIS89
L	GLN93

site_id	CC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CMO I 3161

Chain	Residue
I	PHE39
I	PHE53
I	HIS69
I	VAL73
I	HEM160

site_id	CC4
Number of Residues	15
Details	BINDING SITE FOR RESIDUE HEM J 160

Chain	Residue
J	LEU47
J	PHE48
J	ARG50
J	ARG67
J	LEU72
J	GLN95
J	HIS96
J	ARG99
J	ILE101
J	PHE109
J	GLU138
J	ILE141
J	CMO3162
K	HIS97
K	GLN101

site_id	CC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CMO J 3162

Chain	Residue
J	TRP34
J	PHE48
J	HIS64
J	VAL68
J	HEM160

site_id	CC6
Number of Residues	19
Details	BINDING SITE FOR RESIDUE HEM K 160

Chain	Residue
J	HIS91
J	GLN95
K	LEU53
K	PHE54
K	ARG56
K	VAL57
K	ARG73
K	GLY77
K	LEU78
K	LEU98
K	GLN101
K	HIS102
K	ARG105
K	VAL108
K	HIS112
K	PHE113
K	PHE116
K	LEU144
K	CMO3163

site_id	CC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CMO K 3163

Chain	Residue
K	LEU40
K	HIS70
K	ILE74
K	HEM160

site_id	CC8
Number of Residues	20
Details	BINDING SITE FOR RESIDUE HEM L 160

Chain	Residue
I	HIS96
I	GLN100
L	PRO45
L	PHE46
L	ARG48
L	VAL49
L	HIS62
L	ARG65
L	LEU70
L	LEU90
L	GLN93
L	HIS94
L	ARG97
L	LEU99
L	PHE103
L	PHE104
L	PHE107
L	ILE136
L	CMO3164
L	HOH3181

site_id	CC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE CMO L 3164

Chain	Residue
L	TRP32
L	PHE46
L	HIS62
L	VAL66
L	HEM160

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	861
Details	Domain: {"description":"Globin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00238","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	9
Details	Binding site: {"description":"proximal binding residue"}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)