1X8G
Crystal Structure of the Mono-Zinc Carbapenemase CphA from Aeromonas Hydrophyla
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0008800 | molecular_function | beta-lactamase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0017001 | biological_process | antibiotic catabolic process |
| A | 0042597 | cellular_component | periplasmic space |
| A | 0046677 | biological_process | response to antibiotic |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 401 |
| Chain | Residue |
| A | CO32 |
| A | ASP120 |
| A | CYS221 |
| A | HIS263 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE CO3 A 2 |
| Chain | Residue |
| A | ZN401 |
| A | HOH403 |
| A | HOH404 |
| A | ASP120 |
| A | HIS196 |
| A | CYS221 |
| A | LYS224 |
| A | HIS263 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 3 |
| Chain | Residue |
| A | ARG143 |
| A | ARG143 |
| A | LYS147 |
| A | LYS147 |
| A | HOH560 |
Functional Information from PROSITE/UniProt
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15588826","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17307979","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18563261","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"19651913","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20527888","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15588826","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15588826","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18563261","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20527888","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15588826","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17307979","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20527888","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"15588826","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17307979","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18563261","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 2bmi |
| Chain | Residue | Details |
| A | ASP120 | |
| A | ASN233 |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 2bmi |
| Chain | Residue | Details |
| A | ASP120 |
