Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003756 | molecular_function | protein disulfide isomerase activity |
Functional Information from PROSITE/UniProt
site_id | PS00194 |
Number of Residues | 19 |
Details | THIOREDOXIN_1 Thioredoxin family active site. MVeFYapWCGHCKnLepeW |
Chain | Residue | Details |
A | MET29-TRP47 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 2 |
Details | ACT_SITE: Nucleophile => ECO:0000250 |
Chain | Residue | Details |
A | CYS37 | |
A | CYS40 | |
site_id | SWS_FT_FI2 |
Number of Residues | 2 |
Details | SITE: Contributes to redox potential value => ECO:0000250 |
Chain | Residue | Details |
A | GLY38 | |
A | HIS39 | |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | SITE: Lowers pKa of C-terminal Cys of second active site => ECO:0000250 |
Chain | Residue | Details |
A | ARG103 | |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 4 |
Details | Annotated By Reference To The Literature 1mek |
Chain | Residue | Details |
A | GLY38 | |
A | CYS40 | |
A | HIS39 | |
A | CYS37 | |
site_id | CSA2 |
Number of Residues | 2 |
Details | Annotated By Reference To The Literature 1mek |
Chain | Residue | Details |
A | CYS40 | |
A | CYS37 | |