1X31
Crystal Structure of Heterotetrameric Sarcosine Oxidase from Corynebacterium sp. U-96
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0008115 | molecular_function | sarcosine oxidase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0046653 | biological_process | tetrahydrofolate metabolic process |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008115 | molecular_function | sarcosine oxidase activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0032981 | biological_process | mitochondrial respiratory chain complex I assembly |
| B | 0046653 | biological_process | tetrahydrofolate metabolic process |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008115 | molecular_function | sarcosine oxidase activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 1901053 | biological_process | sarcosine catabolic process |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008115 | molecular_function | sarcosine oxidase activity |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0046653 | biological_process | tetrahydrofolate metabolic process |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 1006 |
| Chain | Residue |
| D | CYS6 |
| D | CYS9 |
| D | HIS59 |
| D | CYS63 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2001 |
| Chain | Residue |
| C | HOH3849 |
| A | GLN30 |
| C | ALA25 |
| C | GLY26 |
| C | GLU27 |
| C | ARG28 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2002 |
| Chain | Residue |
| A | ARG574 |
| A | ALA696 |
| A | ALA697 |
| A | THR722 |
| A | HOH3546 |
| C | ARG176 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2003 |
| Chain | Residue |
| A | ARG597 |
| A | LEU631 |
| A | THR692 |
| A | THR693 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE SO4 D 2004 |
| Chain | Residue |
| D | ARG83 |
| D | HOH4063 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE SO4 C 2005 |
| Chain | Residue |
| A | GLN217 |
| A | ARG219 |
| A | HOH3062 |
| C | VAL199 |
| C | HOH3475 |
| C | HOH4036 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2006 |
| Chain | Residue |
| A | ASN651 |
| A | GLY652 |
| A | SER847 |
| A | LEU849 |
| A | HOH3880 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 2007 |
| Chain | Residue |
| B | PRO8 |
| B | GLU9 |
| B | PHE10 |
| B | ARG181 |
| B | HOH3488 |
| site_id | AC9 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 2008 |
| Chain | Residue |
| A | GLU445 |
| A | LYS446 |
| A | ILE447 |
| A | HOH3988 |
| site_id | BC1 |
| Number of Residues | 36 |
| Details | BINDING SITE FOR RESIDUE FAD B 1001 |
| Chain | Residue |
| B | GLY27 |
| B | GLY29 |
| B | GLY30 |
| B | HIS31 |
| B | GLU52 |
| B | LYS53 |
| B | GLY59 |
| B | ASN60 |
| B | MET61 |
| B | ARG63 |
| B | ASN64 |
| B | THR65 |
| B | THR66 |
| B | ILE67 |
| B | CYS194 |
| B | GLU195 |
| B | VAL196 |
| B | ALA224 |
| B | GLY225 |
| B | ALA226 |
| B | HIS228 |
| B | LEU232 |
| B | LEU247 |
| B | ALA249 |
| B | GLY326 |
| B | GLY353 |
| B | THR354 |
| B | GLY355 |
| B | GLY356 |
| B | PHE357 |
| B | LYS358 |
| B | DMG1005 |
| B | HOH3075 |
| B | HOH3126 |
| B | HOH3531 |
| B | HOH3622 |
| site_id | BC2 |
| Number of Residues | 30 |
| Details | BINDING SITE FOR RESIDUE NAD A 1002 |
| Chain | Residue |
| A | TYR553 |
| A | HOH3001 |
| A | HOH3002 |
| A | HOH3026 |
| A | HOH3135 |
| A | HOH3199 |
| A | HOH3281 |
| A | HOH3354 |
| A | HOH4037 |
| A | GLY134 |
| A | GLY136 |
| A | PRO137 |
| A | ALA138 |
| A | ASP157 |
| A | GLU158 |
| A | ARG159 |
| A | GLY164 |
| A | THR165 |
| A | THR202 |
| A | VAL204 |
| A | ALA247 |
| A | THR248 |
| A | ALA249 |
| A | SER294 |
| A | PHE380 |
| A | GLY416 |
| A | ALA417 |
| A | LEU422 |
| A | ASP423 |
| A | THR424 |
| site_id | BC3 |
| Number of Residues | 22 |
| Details | BINDING SITE FOR RESIDUE FMN B 1004 |
| Chain | Residue |
| A | LYS509 |
| A | ARG510 |
| A | THR516 |
| A | GLN520 |
| A | THR548 |
| A | ARG550 |
| B | ALA62 |
| B | ARG63 |
| B | ASN64 |
| B | THR66 |
| B | HIS172 |
| B | LYS277 |
| B | GLU279 |
| B | ARG322 |
| B | TRP324 |
| B | HOH3030 |
| B | HOH3084 |
| B | HOH3127 |
| B | HOH3272 |
| B | HOH3445 |
| B | HOH3494 |
| B | HOH3502 |
| site_id | BC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE DMG B 1005 |
| Chain | Residue |
| B | THR65 |
| B | ILE67 |
| B | ARG69 |
| B | MET264 |
| B | THR354 |
| B | LYS358 |
| B | FAD1001 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:15946648, ECO:0000269|PubMed:20675294, ECO:0007744|PDB:1VRQ, ECO:0007744|PDB:1X31, ECO:0007744|PDB:3AD7, ECO:0007744|PDB:3AD8, ECO:0007744|PDB:3AD9, ECO:0007744|PDB:3ADA |
| Chain | Residue | Details |
| D | CYS6 | |
| B | GLY356 | |
| B | LYS358 | |
| D | CYS9 | |
| D | HIS59 | |
| D | CYS63 | |
| B | MET61 | |
| B | THR65 | |
| B | ILE67 | |
| B | VAL196 | |
| B | GLY353 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Tele-8alpha-FMN histidine => ECO:0000269|PubMed:11902668, ECO:0000269|PubMed:20675294, ECO:0007744|PDB:3AD7, ECO:0007744|PDB:3AD8, ECO:0007744|PDB:3AD9, ECO:0007744|PDB:3ADA |
| Chain | Residue | Details |
| B | HIS172 | |
| A | GLU783 |
