1X31

Crystal Structure of Heterotetrameric Sarcosine Oxidase from Corynebacterium sp. U-96

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005737	cellular_component	cytoplasm
A	0008115	molecular_function	sarcosine oxidase activity
A	0016491	molecular_function	oxidoreductase activity
A	0046653	biological_process	tetrahydrofolate metabolic process
B	0000166	molecular_function	nucleotide binding
B	0005737	cellular_component	cytoplasm
B	0008115	molecular_function	sarcosine oxidase activity
B	0016491	molecular_function	oxidoreductase activity
B	0046653	biological_process	tetrahydrofolate metabolic process
C	0005737	cellular_component	cytoplasm
C	0008115	molecular_function	sarcosine oxidase activity
C	0016491	molecular_function	oxidoreductase activity
C	1901053	biological_process	sarcosine catabolic process
D	0005737	cellular_component	cytoplasm
D	0008115	molecular_function	sarcosine oxidase activity
D	0016491	molecular_function	oxidoreductase activity
D	0046653	biological_process	tetrahydrofolate metabolic process
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 1006

Chain	Residue
D	CYS6
D	CYS9
D	HIS59
D	CYS63

---

site_id	AC2
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 2001

Chain	Residue
C	HOH3849
A	GLN30
C	ALA25
C	GLY26
C	GLU27
C	ARG28

---

site_id	AC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 A 2002

Chain	Residue
A	ARG574
A	ALA696
A	ALA697
A	THR722
A	HOH3546
C	ARG176

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 2003

Chain	Residue
A	ARG597
A	LEU631
A	THR692
A	THR693

---

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE SO4 D 2004

Chain	Residue
D	ARG83
D	HOH4063

---

site_id	AC6
Number of Residues	6
Details	BINDING SITE FOR RESIDUE SO4 C 2005

Chain	Residue
A	GLN217
A	ARG219
A	HOH3062
C	VAL199
C	HOH3475
C	HOH4036

---

site_id	AC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 2006

Chain	Residue
A	ASN651
A	GLY652
A	SER847
A	LEU849
A	HOH3880

---

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 2007

Chain	Residue
B	PRO8
B	GLU9
B	PHE10
B	ARG181
B	HOH3488

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE SO4 A 2008

Chain	Residue
A	GLU445
A	LYS446
A	ILE447
A	HOH3988

---

site_id	BC1
Number of Residues	36
Details	BINDING SITE FOR RESIDUE FAD B 1001

Chain	Residue
B	GLY27
B	GLY29
B	GLY30
B	HIS31
B	GLU52
B	LYS53
B	GLY59
B	ASN60
B	MET61
B	ARG63
B	ASN64
B	THR65
B	THR66
B	ILE67
B	CYS194
B	GLU195
B	VAL196
B	ALA224
B	GLY225
B	ALA226
B	HIS228
B	LEU232
B	LEU247
B	ALA249
B	GLY326
B	GLY353
B	THR354
B	GLY355
B	GLY356
B	PHE357
B	LYS358
B	DMG1005
B	HOH3075
B	HOH3126
B	HOH3531
B	HOH3622

---

site_id	BC2
Number of Residues	30
Details	BINDING SITE FOR RESIDUE NAD A 1002

Chain	Residue
A	TYR553
A	HOH3001
A	HOH3002
A	HOH3026
A	HOH3135
A	HOH3199
A	HOH3281
A	HOH3354
A	HOH4037
A	GLY134
A	GLY136
A	PRO137
A	ALA138
A	ASP157
A	GLU158
A	ARG159
A	GLY164
A	THR165
A	THR202
A	VAL204
A	ALA247
A	THR248
A	ALA249
A	SER294
A	PHE380
A	GLY416
A	ALA417
A	LEU422
A	ASP423
A	THR424

---

site_id	BC3
Number of Residues	22
Details	BINDING SITE FOR RESIDUE FMN B 1004

Chain	Residue
A	LYS509
A	ARG510
A	THR516
A	GLN520
A	THR548
A	ARG550
B	ALA62
B	ARG63
B	ASN64
B	THR66
B	HIS172
B	LYS277
B	GLU279
B	ARG322
B	TRP324
B	HOH3030
B	HOH3084
B	HOH3127
B	HOH3272
B	HOH3445
B	HOH3494
B	HOH3502

---

site_id	BC4
Number of Residues	7
Details	BINDING SITE FOR RESIDUE DMG B 1005

Chain	Residue
B	THR65
B	ILE67
B	ARG69
B	MET264
B	THR354
B	LYS358
B	FAD1001

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	24
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15946648","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20675294","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1VRQ","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"1X31","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AD7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AD8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AD9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ADA","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	2
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15946648","evidenceCode":"ECO:0000305"},{"source":"PDB","id":"1VRQ","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	Modified residue: {"description":"Tele-8alpha-FMN histidine","evidences":[{"source":"PubMed","id":"11902668","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"20675294","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"3AD7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AD8","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3AD9","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3ADA","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1c0k

Chain	Residue	Details
B	LEU385

---