1X24

Prl-1 (ptp4a)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004721	molecular_function	phosphoprotein phosphatase activity
A	0004725	molecular_function	protein tyrosine phosphatase activity
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005769	cellular_component	early endosome
A	0005783	cellular_component	endoplasmic reticulum
A	0005819	cellular_component	spindle
A	0005886	cellular_component	plasma membrane
A	0006470	biological_process	protein dephosphorylation
A	0009898	cellular_component	cytoplasmic side of plasma membrane
A	0016311	biological_process	dephosphorylation
A	0016787	molecular_function	hydrolase activity
A	0030335	biological_process	positive regulation of cell migration
B	0004721	molecular_function	phosphoprotein phosphatase activity
B	0004725	molecular_function	protein tyrosine phosphatase activity
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005769	cellular_component	early endosome
B	0005783	cellular_component	endoplasmic reticulum
B	0005819	cellular_component	spindle
B	0005886	cellular_component	plasma membrane
B	0006470	biological_process	protein dephosphorylation
B	0009898	cellular_component	cytoplasmic side of plasma membrane
B	0016311	biological_process	dephosphorylation
B	0016787	molecular_function	hydrolase activity
B	0030335	biological_process	positive regulation of cell migration

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	70
Details	Region: {"description":"Interaction with ATF5","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	2
Details	Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Active site: {"description":"Phosphocysteine intermediate","evidences":[{"source":"PROSITE-ProRule","id":"PRU00160","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	12
Details	Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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Catalytic Information from CSA

site_id	CSA1
Number of Residues	3
Details	Annotated By Reference To The Literature 1d5r

Chain	Residue	Details
A	CYS104
A	ARG110
A	ASP72

---

site_id	CSA2
Number of Residues	3
Details	Annotated By Reference To The Literature 1d5r

Chain	Residue	Details
B	CYS104
B	ARG110
B	ASP72

---