1WZO
Crystal Structure of the HpcE from Thermus Thermophilus HB8
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0008704 | molecular_function | 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity |
| A | 0016853 | molecular_function | isomerase activity |
| A | 0018800 | molecular_function | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity |
| A | 1901023 | biological_process | 4-hydroxyphenylacetate catabolic process |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0008704 | molecular_function | 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity |
| B | 0016853 | molecular_function | isomerase activity |
| B | 0018800 | molecular_function | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity |
| B | 1901023 | biological_process | 4-hydroxyphenylacetate catabolic process |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0008704 | molecular_function | 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity |
| C | 0016853 | molecular_function | isomerase activity |
| C | 0018800 | molecular_function | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity |
| C | 1901023 | biological_process | 4-hydroxyphenylacetate catabolic process |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0008704 | molecular_function | 5-carboxymethyl-2-hydroxymuconate delta-isomerase activity |
| D | 0016853 | molecular_function | isomerase activity |
| D | 0018800 | molecular_function | 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase activity |
| D | 1901023 | biological_process | 4-hydroxyphenylacetate catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 1007 |
| Chain | Residue |
| A | GLU97 |
| A | GLU99 |
| A | ASP128 |
| A | LYS146 |
| A | HOH1012 |
| A | HOH1030 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1008 |
| Chain | Residue |
| D | ARG140 |
| D | PRO141 |
| D | HOH1189 |
| D | HOH1210 |
| D | HOH1214 |
| C | ARG140 |
| D | ALA50 |
| D | LEU51 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 1001 |
| Chain | Residue |
| A | VAL120 |
| A | LEU121 |
| A | VAL160 |
| A | GLU161 |
| A | VAL163 |
| A | HOH1024 |
| A | HOH1143 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL A 1002 |
| Chain | Residue |
| A | TRP37 |
| A | HIS81 |
| A | PHE157 |
| A | GLY236 |
| A | ALA237 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL B 1003 |
| Chain | Residue |
| B | TRP37 |
| B | HIS81 |
| B | PHE157 |
| B | GLY236 |
| B | ALA237 |
| B | HOH1200 |
| B | HOH1202 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL B 1004 |
| Chain | Residue |
| B | VAL120 |
| B | LEU121 |
| B | GLY122 |
| B | TYR123 |
| B | VAL160 |
| B | GLU161 |
| B | VAL163 |
| B | HOH1040 |
| B | HOH1114 |
| site_id | AC7 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL C 1005 |
| Chain | Residue |
| C | TYR17 |
| C | TRP37 |
| C | HIS81 |
| C | PHE157 |
| C | GLY236 |
| C | ALA237 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE GOL D 1006 |
| Chain | Residue |
| D | TYR17 |
| D | TRP37 |
| D | HIS81 |
| D | PHE157 |
| D | GLY236 |
| D | ALA237 |
