Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004392 | molecular_function | heme oxygenase (decyclizing) activity |
| A | 0006788 | biological_process | heme oxidation |
| A | 0006979 | biological_process | response to oxidative stress |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0020037 | molecular_function | heme binding |
| A | 0042167 | biological_process | heme catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0004392 | molecular_function | heme oxygenase (decyclizing) activity |
| B | 0006788 | biological_process | heme oxidation |
| B | 0006979 | biological_process | response to oxidative stress |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0020037 | molecular_function | heme binding |
| B | 0042167 | biological_process | heme catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 701 |
| Chain | Residue |
| A | ARG112 |
| A | HIS192 |
| A | HOH978 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 702 |
| Chain | Residue |
| B | SER26 |
| B | THR27 |
| B | HIS205 |
| B | HOH960 |
| B | HOH976 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE SO4 A 703 |
| Chain | Residue |
| A | HOH1122 |
| A | HOH1143 |
| A | GLN58 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE SO4 A 704 |
| Chain | Residue |
| A | GLN58 |
| A | HOH936 |
| A | HOH951 |
| A | HOH1011 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 B 705 |
| Chain | Residue |
| B | ASP61 |
| B | GOL804 |
| B | HOH955 |
| B | HOH998 |
| B | HOH1075 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 706 |
| Chain | Residue |
| A | SER26 |
| A | THR27 |
| A | HIS205 |
| A | HOH931 |
| A | HOH1118 |
| site_id | AC7 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR RESIDUE YOK A 901 |
| Chain | Residue |
| A | LYS13 |
| A | HIS20 |
| A | GLU24 |
| A | TYR130 |
| A | VAL131 |
| A | ARG132 |
| A | GLY135 |
| A | SER138 |
| A | GLY139 |
| A | ARG177 |
| A | PHE201 |
| A | ASN204 |
| A | PHE208 |
| A | HOH971 |
| A | HOH990 |
| A | HOH1116 |
| site_id | AC8 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE YOK B 902 |
| Chain | Residue |
| B | HIS20 |
| B | GLU24 |
| B | VAL131 |
| B | GLY135 |
| B | SER138 |
| B | GLY139 |
| B | LYS173 |
| B | ARG177 |
| B | PHE201 |
| B | ASN204 |
| B | PHE208 |
| B | HOH957 |
| B | HOH990 |
| B | HOH1084 |
| B | HOH1101 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE GOL B 801 |
| Chain | Residue |
| B | ALA9 |
| B | LYS13 |
| B | ARG177 |
| B | HOH1022 |
| B | HOH1101 |
| site_id | BC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 802 |
| Chain | Residue |
| A | SER94 |
| A | GLU95 |
| A | SER98 |
| A | HOH1021 |
| site_id | BC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL B 803 |
| Chain | Residue |
| B | SER30 |
| B | LYS34 |
| B | HOH918 |
| B | HOH1145 |
| site_id | BC3 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE GOL B 804 |
| site_id | BC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE GOL A 805 |
| Chain | Residue |
| A | PRO75 |
| A | ASN78 |
| A | GLU81 |
| A | HOH943 |
Functional Information from PROSITE/UniProt
| site_id | PS00593 |
| Number of Residues | 11 |
| Details | HEME_OXYGENASE Heme oxygenase signature. LVAHHYVRYLG |
| Chain | Residue | Details |
| A | LEU125-GLY135 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: axial binding residue => ECO:0000250 |
| Chain | Residue | Details |
| A | HIS20 | |
| B | HIS20 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1wnw |
| Chain | Residue | Details |
| A | ASP136 | |
| A | GLY140 | |
| site_id | CSA2 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1wnw |
| Chain | Residue | Details |
| B | ASP136 | |
| B | GLY140 | |
| site_id | MCSA1 |
| Number of Residues | 7 |
| Details | M-CSA 795 |
| Chain | Residue | Details |
| A | HIS25 | metal ligand |
| A | TYR53 | activator, electrostatic stabiliser |
| A | VAL131 | activator |
| A | ARG132 | activator |
| A | GLY135 | steric role |
| A | ASP136 | modifies pKa |
| A | GLY140 | steric role |
| site_id | MCSA2 |
| Number of Residues | 7 |
| Details | M-CSA 795 |
| Chain | Residue | Details |
| B | HIS25 | metal ligand |
| B | TYR53 | activator, electrostatic stabiliser |
| B | VAL131 | activator |
| B | ARG132 | activator |
| B | GLY135 | steric role |
| B | ASP136 | modifies pKa |
| B | GLY140 | steric role |
