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1WZ9

The 2.1 A structure of a tumour suppressing serpin

Functional Information from GO Data
ChainGOidnamespacecontents
A0001533cellular_componentcornified envelope
A0002009biological_processmorphogenesis of an epithelium
A0004867molecular_functionserine-type endopeptidase inhibitor activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005737cellular_componentcytoplasm
A0016528cellular_componentsarcoplasm
A0030198biological_processextracellular matrix organization
A0050678biological_processregulation of epithelial cell proliferation
A0060512biological_processprostate gland morphogenesis
B0001533cellular_componentcornified envelope
B0002009biological_processmorphogenesis of an epithelium
B0004867molecular_functionserine-type endopeptidase inhibitor activity
B0005515molecular_functionprotein binding
B0005576cellular_componentextracellular region
B0005615cellular_componentextracellular space
B0005737cellular_componentcytoplasm
B0016528cellular_componentsarcoplasm
B0030198biological_processextracellular matrix organization
B0050678biological_processregulation of epithelial cell proliferation
B0060512biological_processprostate gland morphogenesis
Functional Information from PDB Data
site_idAC1
Number of Residues6
DetailsBINDING SITE FOR RESIDUE SO4 A 1001
ChainResidue
AGLY26
AASN27
ALYS280
AHOH1024
BGLY331
BASP332

Functional Information from PROSITE/UniProt
site_idPS00284
Number of Residues11
DetailsSERPIN Serpins signature. LNADHPFIYiI
ChainResidueDetails
ALEU348-ILE358

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues2
DetailsSITE: Reactive bond homolog => ECO:0000250
ChainResidueDetails
AARG340
BARG340

site_idSWS_FT_FI2
Number of Residues8
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255
ChainResidueDetails
AASN99
AASN133
AASN188
AASN361
BASN99
BASN133
BASN188
BASN361

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PDB entries from 2025-06-18

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