1WYD
Crystal Structure of Aspartyl-tRNA synthetase from Sulfolobus tokodaii
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0003676 | molecular_function | nucleic acid binding |
| A | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| A | 0004815 | molecular_function | aspartate-tRNA ligase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006412 | biological_process | translation |
| A | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| A | 0006422 | biological_process | aspartyl-tRNA aminoacylation |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0050560 | molecular_function | aspartate-tRNA(Asn) ligase activity |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0003676 | molecular_function | nucleic acid binding |
| B | 0004812 | molecular_function | aminoacyl-tRNA ligase activity |
| B | 0004815 | molecular_function | aspartate-tRNA ligase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006412 | biological_process | translation |
| B | 0006418 | biological_process | tRNA aminoacylation for protein translation |
| B | 0006422 | biological_process | aspartyl-tRNA aminoacylation |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0050560 | molecular_function | aspartate-tRNA(Asn) ligase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 431 |
| Chain | Residue |
| A | THR166 |
| A | GLU167 |
| A | GLN186 |
| A | HOH1038 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1001 |
| Chain | Residue |
| A | PRO217 |
| A | PHE218 |
| A | SER413 |
| A | VAL414 |
| A | LYS415 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL B 430 |
| Chain | Residue |
| B | THR166 |
| B | GLU167 |
| B | GLN186 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1002 |
| Chain | Residue |
| B | THR216 |
| B | PRO217 |
| B | PHE218 |
| B | SER413 |
| B | VAL414 |
| B | LYS415 |
| B | HOH1152 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EPE A 1003 |
| Chain | Residue |
| A | PHE218 |
| A | HIS219 |
| A | LEU220 |
| A | PHE223 |
| A | ARG403 |
| A | VAL414 |
| A | HOH1027 |
| A | HOH1057 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE EPE B 1004 |
| Chain | Residue |
| B | PHE218 |
| B | HIS219 |
| B | LEU220 |
| B | PHE223 |
| B | ARG403 |
| B | HOH1046 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 12 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_02075 |
| Chain | Residue | Details |
| A | GLU167 | |
| B | SER355 | |
| B | ARG359 | |
| B | GLY400 | |
| A | ARG210 | |
| A | GLU352 | |
| A | SER355 | |
| A | ARG359 | |
| A | GLY400 | |
| B | GLU167 | |
| B | ARG210 | |
| B | GLU352 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | SITE: Important for tRNA non-discrimination => ECO:0000255|HAMAP-Rule:MF_02075 |
| Chain | Residue | Details |
| A | PRO82 | |
| B | PRO82 |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1asy |
| Chain | Residue | Details |
| A | ARG403 | |
| A | ARG210 | |
| A | ASP227 |
| site_id | CSA2 |
| Number of Residues | 3 |
| Details | Annotated By Reference To The Literature 1asy |
| Chain | Residue | Details |
| B | ARG403 | |
| B | ARG210 | |
| B | ASP227 |
| site_id | CSA3 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1asy |
| Chain | Residue | Details |
| A | ARG210 |
| site_id | CSA4 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1asy |
| Chain | Residue | Details |
| B | ARG210 |
