1WWR

Crystal structure of tRNA adenosine deaminase TadA from Aquifex aeolicus

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002100	biological_process	tRNA wobble adenosine to inosine editing
A	0003824	molecular_function	catalytic activity
A	0008033	biological_process	tRNA processing
A	0008251	molecular_function	tRNA-specific adenosine deaminase activity
A	0008270	molecular_function	zinc ion binding
A	0016787	molecular_function	hydrolase activity
A	0046872	molecular_function	metal ion binding
A	0052717	molecular_function	tRNA-specific adenosine-34 deaminase activity
B	0002100	biological_process	tRNA wobble adenosine to inosine editing
B	0003824	molecular_function	catalytic activity
B	0008033	biological_process	tRNA processing
B	0008251	molecular_function	tRNA-specific adenosine deaminase activity
B	0008270	molecular_function	zinc ion binding
B	0016787	molecular_function	hydrolase activity
B	0046872	molecular_function	metal ion binding
B	0052717	molecular_function	tRNA-specific adenosine-34 deaminase activity
C	0002100	biological_process	tRNA wobble adenosine to inosine editing
C	0003824	molecular_function	catalytic activity
C	0008033	biological_process	tRNA processing
C	0008251	molecular_function	tRNA-specific adenosine deaminase activity
C	0008270	molecular_function	zinc ion binding
C	0016787	molecular_function	hydrolase activity
C	0046872	molecular_function	metal ion binding
C	0052717	molecular_function	tRNA-specific adenosine-34 deaminase activity
D	0002100	biological_process	tRNA wobble adenosine to inosine editing
D	0003824	molecular_function	catalytic activity
D	0008033	biological_process	tRNA processing
D	0008251	molecular_function	tRNA-specific adenosine deaminase activity
D	0008270	molecular_function	zinc ion binding
D	0016787	molecular_function	hydrolase activity
D	0046872	molecular_function	metal ion binding
D	0052717	molecular_function	tRNA-specific adenosine-34 deaminase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 201

Chain	Residue
A	HIS52
A	CYS82
A	CYS85
A	HOH225

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site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN B 202

Chain	Residue
B	HIS52
B	CYS82
B	CYS85
B	HOH333

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site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 203

Chain	Residue
C	CYS82
C	CYS85
C	HOH329
C	HIS52

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site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN D 204

Chain	Residue
D	HIS52
D	CYS82
D	CYS85
D	HOH241

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Functional Information from PROSITE/UniProt

site_id	PS00903
Number of Residues	38
Details	CYT_DCMP_DEAMINASES_1 Cytidine and deoxycytidylate deaminases zinc-binding region signature. HAEmlAIkeacrrlntkylegcelyvtle...........PCim......CsyaL

Chain	Residue	Details
A	HIS52-LEU89

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton donor => ECO:0000255|HAMAP-Rule:MF_00972

Chain	Residue	Details
A	GLU54
B	GLU54
C	GLU54
D	GLU54

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site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00972, ECO:0000269|PubMed:15677468

Chain	Residue	Details
A	HIS52
D	HIS52
D	CYS82
D	CYS85
A	CYS82
A	CYS85
B	HIS52
B	CYS82
B	CYS85
C	HIS52
C	CYS82
C	CYS85

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