1WWR
Crystal structure of tRNA adenosine deaminase TadA from Aquifex aeolicus
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0002100 | biological_process | tRNA wobble adenosine to inosine editing |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0008033 | biological_process | tRNA processing |
| A | 0008251 | molecular_function | tRNA-specific adenosine deaminase activity |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0052717 | molecular_function | tRNA-specific adenosine-34 deaminase activity |
| B | 0002100 | biological_process | tRNA wobble adenosine to inosine editing |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0008033 | biological_process | tRNA processing |
| B | 0008251 | molecular_function | tRNA-specific adenosine deaminase activity |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0052717 | molecular_function | tRNA-specific adenosine-34 deaminase activity |
| C | 0002100 | biological_process | tRNA wobble adenosine to inosine editing |
| C | 0003824 | molecular_function | catalytic activity |
| C | 0008033 | biological_process | tRNA processing |
| C | 0008251 | molecular_function | tRNA-specific adenosine deaminase activity |
| C | 0008270 | molecular_function | zinc ion binding |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0046872 | molecular_function | metal ion binding |
| C | 0052717 | molecular_function | tRNA-specific adenosine-34 deaminase activity |
| D | 0002100 | biological_process | tRNA wobble adenosine to inosine editing |
| D | 0003824 | molecular_function | catalytic activity |
| D | 0008033 | biological_process | tRNA processing |
| D | 0008251 | molecular_function | tRNA-specific adenosine deaminase activity |
| D | 0008270 | molecular_function | zinc ion binding |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0046872 | molecular_function | metal ion binding |
| D | 0052717 | molecular_function | tRNA-specific adenosine-34 deaminase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 201 |
| Chain | Residue |
| A | HIS52 |
| A | CYS82 |
| A | CYS85 |
| A | HOH225 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 202 |
| Chain | Residue |
| B | HIS52 |
| B | CYS82 |
| B | CYS85 |
| B | HOH333 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN C 203 |
| Chain | Residue |
| C | CYS82 |
| C | CYS85 |
| C | HOH329 |
| C | HIS52 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN D 204 |
| Chain | Residue |
| D | HIS52 |
| D | CYS82 |
| D | CYS85 |
| D | HOH241 |
Functional Information from PROSITE/UniProt
| site_id | PS00903 |
| Number of Residues | 38 |
| Details | CYT_DCMP_DEAMINASES_1 Cytidine and deoxycytidylate deaminases zinc-binding region signature. HAEmlAIkeacrrlntkylegcelyvtle...........PCim......CsyaL |
| Chain | Residue | Details |
| A | HIS52-LEU89 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 440 |
| Details | Domain: {"description":"CMP/dCMP-type deaminase","evidences":[{"source":"PROSITE-ProRule","id":"PRU01083","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_00972","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 12 |
| Details | Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00972","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15677468","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
