1WRY

Solution structure of the SH3 domain-binding glutamic acid-rich-like protein

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005515	molecular_function	protein binding
A	0005615	cellular_component	extracellular space
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0005886	cellular_component	plasma membrane
A	0017124	molecular_function	SH3 domain binding
A	0043161	biological_process	proteasome-mediated ubiquitin-dependent protein catabolic process
A	0070062	cellular_component	extracellular exosome
A	0140517	molecular_function	protein-RNA adaptor activity
A	1904690	biological_process	positive regulation of cytoplasmic translational initiation
A	1990756	molecular_function	ubiquitin-like ligase-substrate adaptor activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	37
Details	Region: {"description":"Required for interaction with HER2","evidences":[{"source":"PubMed","id":"32381043","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	17
Details	Region: {"description":"Required for interaction with PFN1, HER2, and ATG12","evidences":[{"source":"PubMed","id":"32381043","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34331014","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"34870550","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	6
Details	Motif: {"description":"SH3-binding","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

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