1WRV

Crystal Structure of T.th.HB8 Branched-Chain Amino Acid Aminotransferase

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003824	molecular_function	catalytic activity
A	0004084	molecular_function	branched-chain-amino-acid transaminase activity
A	0005829	cellular_component	cytosol
A	0006532	biological_process	aspartate biosynthetic process
A	0008483	molecular_function	transaminase activity
A	0008652	biological_process	amino acid biosynthetic process
A	0009081	biological_process	branched-chain amino acid metabolic process
A	0009082	biological_process	branched-chain amino acid biosynthetic process
A	0009097	biological_process	isoleucine biosynthetic process
A	0009098	biological_process	L-leucine biosynthetic process
A	0009099	biological_process	valine biosynthetic process
A	0046394	biological_process	carboxylic acid biosynthetic process
A	0050048	molecular_function	L-leucine:2-oxoglutarate aminotransferase activity
A	0052654	molecular_function	L-leucine transaminase activity
A	0052655	molecular_function	L-valine transaminase activity
A	0052656	molecular_function	L-isoleucine transaminase activity
B	0003824	molecular_function	catalytic activity
B	0004084	molecular_function	branched-chain-amino-acid transaminase activity
B	0005829	cellular_component	cytosol
B	0006532	biological_process	aspartate biosynthetic process
B	0008483	molecular_function	transaminase activity
B	0008652	biological_process	amino acid biosynthetic process
B	0009081	biological_process	branched-chain amino acid metabolic process
B	0009082	biological_process	branched-chain amino acid biosynthetic process
B	0009097	biological_process	isoleucine biosynthetic process
B	0009098	biological_process	L-leucine biosynthetic process
B	0009099	biological_process	valine biosynthetic process
B	0046394	biological_process	carboxylic acid biosynthetic process
B	0050048	molecular_function	L-leucine:2-oxoglutarate aminotransferase activity
B	0052654	molecular_function	L-leucine transaminase activity
B	0052655	molecular_function	L-valine transaminase activity
B	0052656	molecular_function	L-isoleucine transaminase activity
C	0003824	molecular_function	catalytic activity
C	0004084	molecular_function	branched-chain-amino-acid transaminase activity
C	0005829	cellular_component	cytosol
C	0006532	biological_process	aspartate biosynthetic process
C	0008483	molecular_function	transaminase activity
C	0008652	biological_process	amino acid biosynthetic process
C	0009081	biological_process	branched-chain amino acid metabolic process
C	0009082	biological_process	branched-chain amino acid biosynthetic process
C	0009097	biological_process	isoleucine biosynthetic process
C	0009098	biological_process	L-leucine biosynthetic process
C	0009099	biological_process	valine biosynthetic process
C	0046394	biological_process	carboxylic acid biosynthetic process
C	0050048	molecular_function	L-leucine:2-oxoglutarate aminotransferase activity
C	0052654	molecular_function	L-leucine transaminase activity
C	0052655	molecular_function	L-valine transaminase activity
C	0052656	molecular_function	L-isoleucine transaminase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 420

Chain	Residue
A	ARG68
C	GLU173
C	ARG269
C	HOH1437

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL B 920

Chain	Residue
A	GLU173
B	ARG269
B	HOH959
C	ARG68

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE CL A 1420

Chain	Residue
A	HOH1451
B	ARG68
B	GLU173
A	ARG269

---

site_id	AC4
Number of Residues	15
Details	BINDING SITE FOR RESIDUE PLP A 413

Chain	Residue
A	ARG59
A	ARG148
A	LYS159
A	TYR164
A	GLU193
A	GLY196
A	LEU216
A	GLY218
A	ILE219
A	THR220
A	GLY255
A	THR256
A	MPD414
A	HOH1422
A	HOH1452

---

site_id	AC5
Number of Residues	15
Details	BINDING SITE FOR RESIDUE PLP B 913

Chain	Residue
B	ARG59
B	ARG148
B	LYS159
B	TYR164
B	GLU193
B	GLY196
B	LEU216
B	GLY218
B	ILE219
B	THR220
B	GLY255
B	THR256
B	MPD914
B	HOH925
B	HOH943

---

site_id	AC6
Number of Residues	15
Details	BINDING SITE FOR RESIDUE PLP C 1413

Chain	Residue
C	ARG59
C	ARG148
C	LYS159
C	TYR164
C	GLU193
C	GLY196
C	LEU216
C	GLY218
C	ILE219
C	THR220
C	GLY255
C	THR256
C	MPD1414
C	HOH1416
C	HOH1468

---

site_id	AC7
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MPD A 414

Chain	Residue
A	TYR164
A	GLY196
A	ALA257
A	PLP413
A	HOH1464
C	VAL109

---

site_id	AC8
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MPD B 914

Chain	Residue
B	LEU107
B	GLY196
B	PLP913
B	MPD915
B	HOH931
B	HOH1030

---

site_id	AC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MPD C 1414

Chain	Residue
C	TYR164
C	GLY196
C	PLP1413
C	HOH1462

---

site_id	BC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MPD A 415

Chain	Residue
A	ASP230
C	ARG295
C	HOH1518

---

site_id	BC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MPD B 915

Chain	Residue
B	TRP124
B	TRP126
B	MPD914
B	HOH921

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