1WQ8

Crystal structure of Vammin, a VEGF-F from a snake venom

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001666	biological_process	response to hypoxia
A	0001938	biological_process	positive regulation of endothelial cell proliferation
A	0002040	biological_process	sprouting angiogenesis
A	0005172	molecular_function	vascular endothelial growth factor receptor binding
A	0005576	cellular_component	extracellular region
A	0005615	cellular_component	extracellular space
A	0008083	molecular_function	growth factor activity
A	0016020	cellular_component	membrane
A	0038084	biological_process	vascular endothelial growth factor signaling pathway
A	0042056	molecular_function	chemoattractant activity
A	0044551	biological_process	venom-mediated vasodilation
A	0045766	biological_process	positive regulation of angiogenesis
A	0048010	biological_process	vascular endothelial growth factor receptor signaling pathway
A	0050918	biological_process	positive chemotaxis
A	0050930	biological_process	induction of positive chemotaxis
A	0060754	biological_process	positive regulation of mast cell chemotaxis
A	0090729	molecular_function	toxin activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE TRS A 1173

Chain	Residue
A	LEU20
A	PRO22
A	GLY47
A	CYS48
A	HOH1008
A	HOH1045
A	HOH1071
A	HOH1081
A	HOH1118

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Functional Information from PROSITE/UniProt

site_id	PS00249
Number of Residues	13
Details	PDGF_1 Platelet-derived growth factor (PDGF) family signature. PSCVavlRCSGCC

Chain	Residue	Details
A	PRO37-CYS49

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