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1WQ8

Crystal structure of Vammin, a VEGF-F from a snake venom

Functional Information from GO Data
ChainGOidnamespacecontents
A0001666biological_processresponse to hypoxia
A0001938biological_processpositive regulation of endothelial cell proliferation
A0002040biological_processsprouting angiogenesis
A0005172molecular_functionvascular endothelial growth factor receptor binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0008083molecular_functiongrowth factor activity
A0016020cellular_componentmembrane
A0038084biological_processvascular endothelial growth factor signaling pathway
A0042056molecular_functionchemoattractant activity
A0044496biological_processnegative regulation of blood pressure in another organism
A0045766biological_processpositive regulation of angiogenesis
A0048010biological_processvascular endothelial growth factor receptor signaling pathway
A0050918biological_processpositive chemotaxis
A0050930biological_processinduction of positive chemotaxis
A0060754biological_processpositive regulation of mast cell chemotaxis
A0090729molecular_functiontoxin activity
Functional Information from PDB Data
site_idAC1
Number of Residues9
DetailsBINDING SITE FOR RESIDUE TRS A 1173
ChainResidue
ALEU20
APRO22
AGLY47
ACYS48
AHOH1008
AHOH1045
AHOH1071
AHOH1081
AHOH1118

Functional Information from PROSITE/UniProt
site_idPS00249
Number of Residues13
DetailsPDGF_1 Platelet-derived growth factor (PDGF) family signature. PSCVavlRCSGCC
ChainResidueDetails
APRO37-CYS49

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsMOD_RES: Pyrrolidone carboxylic acid => ECO:0000269|PubMed:15542594
ChainResidueDetails
APCA1

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PDB entries from 2024-11-06

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