Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0016054 | biological_process | organic acid catabolic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0050661 | molecular_function | NADP binding |
| A | 0051287 | molecular_function | NAD binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0016054 | biological_process | organic acid catabolic process |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0050661 | molecular_function | NADP binding |
| B | 0051287 | molecular_function | NAD binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0016054 | biological_process | organic acid catabolic process |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0050661 | molecular_function | NADP binding |
| C | 0051287 | molecular_function | NAD binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0016054 | biological_process | organic acid catabolic process |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0050661 | molecular_function | NADP binding |
| D | 0051287 | molecular_function | NAD binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE SO4 A 1305 |
| Chain | Residue |
| A | SER117 |
| A | GLY118 |
| A | GLY119 |
| A | LYS165 |
| A | ASN169 |
| A | NDP1301 |
| A | HOH1428 |
| B | SER204 |
| site_id | AC2 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 B 1306 |
| Chain | Residue |
| B | SER117 |
| B | GLY118 |
| B | GLY119 |
| B | LYS165 |
| B | ASN169 |
| B | NDP1302 |
| B | HOH1321 |
| B | HOH1446 |
| A | SER204 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE SO4 C 1307 |
| Chain | Residue |
| C | SER117 |
| C | GLY118 |
| C | GLY119 |
| C | LYS165 |
| C | ASN169 |
| C | NDP1303 |
| C | HOH1362 |
| C | HOH1375 |
| D | SER204 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE SO4 D 1308 |
| Chain | Residue |
| D | SER117 |
| D | GLY118 |
| D | GLY119 |
| D | LYS165 |
| D | NDP1304 |
| D | HOH1395 |
| D | HOH1494 |
| site_id | AC5 |
| Number of Residues | 33 |
| Details | BINDING SITE FOR RESIDUE NDP A 1301 |
| Chain | Residue |
| A | GLY8 |
| A | LEU9 |
| A | GLY10 |
| A | ALA11 |
| A | MET12 |
| A | ASN30 |
| A | ARG31 |
| A | THR32 |
| A | LYS35 |
| A | CYS62 |
| A | LEU63 |
| A | PRO64 |
| A | GLU68 |
| A | GLU71 |
| A | THR90 |
| A | SER91 |
| A | VAL116 |
| A | GLY119 |
| A | LYS165 |
| A | THR226 |
| A | PHE227 |
| A | LYS234 |
| A | SO41305 |
| A | HOH1306 |
| A | HOH1307 |
| A | HOH1310 |
| A | HOH1314 |
| A | HOH1348 |
| A | HOH1354 |
| A | HOH1356 |
| A | HOH1386 |
| A | HOH1456 |
| A | HOH1460 |
| site_id | AC6 |
| Number of Residues | 32 |
| Details | BINDING SITE FOR RESIDUE NDP C 1303 |
| Chain | Residue |
| C | GLY8 |
| C | LEU9 |
| C | GLY10 |
| C | ALA11 |
| C | MET12 |
| C | ASN30 |
| C | ARG31 |
| C | THR32 |
| C | CYS62 |
| C | LEU63 |
| C | PRO64 |
| C | GLU68 |
| C | GLU71 |
| C | SER91 |
| C | VAL116 |
| C | GLY119 |
| C | THR226 |
| C | PHE227 |
| C | LYS234 |
| C | SO41307 |
| C | HOH1312 |
| C | HOH1315 |
| C | HOH1327 |
| C | HOH1329 |
| C | HOH1332 |
| C | HOH1355 |
| C | HOH1400 |
| C | HOH1402 |
| C | HOH1413 |
| C | HOH1447 |
| C | HOH1464 |
| D | ARG105 |
| site_id | AC7 |
| Number of Residues | 25 |
| Details | BINDING SITE FOR RESIDUE NDP D 1304 |
| Chain | Residue |
| D | GLY10 |
| D | ALA11 |
| D | MET12 |
| D | ASN30 |
| D | ARG31 |
| D | THR32 |
| D | CYS62 |
| D | LEU63 |
| D | PRO64 |
| D | GLU68 |
| D | THR90 |
| D | SER91 |
| D | VAL116 |
| D | LYS165 |
| D | LYS234 |
| D | SO41308 |
| D | HOH1330 |
| D | HOH1345 |
| D | HOH1351 |
| D | HOH1360 |
| D | HOH1395 |
| D | HOH1465 |
| D | HOH1476 |
| D | HOH1484 |
| D | LEU9 |
| site_id | AC8 |
| Number of Residues | 28 |
| Details | BINDING SITE FOR RESIDUE NDP B 1302 |
| Chain | Residue |
| B | GLY8 |
| B | LEU9 |
| B | GLY10 |
| B | ALA11 |
| B | MET12 |
| B | ASN30 |
| B | ARG31 |
| B | THR32 |
| B | CYS62 |
| B | LEU63 |
| B | PRO64 |
| B | GLU68 |
| B | GLU71 |
| B | THR90 |
| B | SER91 |
| B | VAL116 |
| B | GLY119 |
| B | THR226 |
| B | PHE227 |
| B | LYS234 |
| B | SO41306 |
| B | HOH1317 |
| B | HOH1324 |
| B | HOH1326 |
| B | HOH1330 |
| B | HOH1351 |
| B | HOH1355 |
| B | HOH1378 |
Functional Information from PROSITE/UniProt
| site_id | PS00895 |
| Number of Residues | 14 |
| Details | 3_HYDROXYISOBUT_DH 3-hydroxyisobutyrate dehydrogenase signature. FIGLGaMGypMAgH |
| Chain | Residue | Details |
| A | PHE6-HIS19 | |
