1WL8

Crystal structure of PH1346 protein from Pyrococcus horikoshii

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003921	molecular_function	GMP synthase activity
A	0003922	molecular_function	GMP synthase (glutamine-hydrolyzing) activity
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0006177	biological_process	GMP biosynthetic process
A	0006541	biological_process	glutamine metabolic process
A	0016874	molecular_function	ligase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	6
Details	BINDING SITE FOR RESIDUE CL A 1202

Chain	Residue
A	GLY10
A	GLN11
A	TYR12
A	HIS166
A	HOH1212
A	HOH1283

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site_id	AC2
Number of Residues	7
Details	BINDING SITE FOR RESIDUE ACY A 1201

Chain	Residue
A	ARG121
A	GLU157
A	HOH1265
A	HOH1273
A	HIS14
A	GLU105
A	GLU107

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000255|HAMAP-Rule:MF_01510

Chain	Residue	Details
A	CYS79

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site_id	SWS_FT_FI2
Number of Residues	2
Details	ACT_SITE: ACT_SITE => ECO:0000255|HAMAP-Rule:MF_01510

Chain	Residue	Details
A	HIS166
A	GLU168

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