1WKQ
Crystal Structure of Bacillus subtilis Guanine Deaminase. The first domain-swapped structure in the cytidine deaminase superfamily
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0006144 | biological_process | purine nucleobase metabolic process |
| A | 0006147 | biological_process | guanine catabolic process |
| A | 0006152 | biological_process | purine nucleoside catabolic process |
| A | 0008270 | molecular_function | zinc ion binding |
| A | 0008892 | molecular_function | guanine deaminase activity |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0047974 | molecular_function | guanosine deaminase activity |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0006144 | biological_process | purine nucleobase metabolic process |
| B | 0006147 | biological_process | guanine catabolic process |
| B | 0006152 | biological_process | purine nucleoside catabolic process |
| B | 0008270 | molecular_function | zinc ion binding |
| B | 0008892 | molecular_function | guanine deaminase activity |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
| B | 0047974 | molecular_function | guanosine deaminase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN A 201 |
| Chain | Residue |
| A | HIS53 |
| A | CYS83 |
| A | CYS86 |
| A | HOH1302 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE ZN B 202 |
| Chain | Residue |
| B | HIS53 |
| B | CYS83 |
| B | CYS86 |
| B | HOH1303 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE IMD A 1301 |
| Chain | Residue |
| A | ASN42 |
| A | HIS53 |
| A | ASP114 |
| A | HOH1303 |
| B | TRP92 |
| B | TYR156 |
| A | PHE26 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE IMD B 1302 |
| Chain | Residue |
| A | TRP92 |
| A | TYR156 |
| B | PHE26 |
| B | ASN42 |
| B | HIS53 |
| B | ASP114 |
| B | HOH1304 |
Functional Information from PROSITE/UniProt
| site_id | PS00903 |
| Number of Residues | 38 |
| Details | CYT_DCMP_DEAMINASES_1 Cytidine and deoxycytidylate deaminases zinc-binding region signature. HAEvtAIrkackvlgayqlddcilytsce...........PCpm......ClgaI |
| Chain | Residue | Details |
| A | HIS53-ILE90 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 131 |
| Details | Domain: {"description":"CMP/dCMP-type deaminase","evidences":[{"source":"PROSITE-ProRule","id":"PRU01083","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton donor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Binding site: {} |
| Chain | Residue | Details |
