Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006796 | biological_process | phosphate-containing compound metabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0004427 | molecular_function | inorganic diphosphate phosphatase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0006796 | biological_process | phosphate-containing compound metabolic process |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN A 287 |
| Chain | Residue |
| A | ASP115 |
| A | ASP120 |
| A | ASP152 |
| A | MN288 |
| A | PO4292 |
| A | HOH293 |
| A | HOH294 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN A 288 |
| Chain | Residue |
| A | ASP120 |
| A | MN287 |
| A | PO4292 |
| A | HOH293 |
| A | HOH295 |
| A | HOH296 |
| A | HOH297 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 289 |
| Chain | Residue |
| A | GLU58 |
| A | PO4291 |
| A | PO4292 |
| A | HOH298 |
| A | HOH299 |
| A | HOH300 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN A 290 |
| Chain | Residue |
| A | ASP147 |
| A | ASP152 |
| A | PO4291 |
| A | PO4292 |
| A | HOH301 |
| A | HOH302 |
| site_id | AC5 |
| Number of Residues | 13 |
| Details | BINDING SITE FOR RESIDUE PO4 A 291 |
| Chain | Residue |
| A | LYS56 |
| A | GLU58 |
| A | ARG78 |
| A | ASP147 |
| A | TYR192 |
| A | LYS193 |
| A | MN289 |
| A | MN290 |
| A | PO4292 |
| A | HOH298 |
| A | HOH301 |
| A | HOH351 |
| A | HOH388 |
| site_id | AC6 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR RESIDUE PO4 A 292 |
| Chain | Residue |
| A | LYS56 |
| A | GLU58 |
| A | TYR93 |
| A | ASP115 |
| A | ASP120 |
| A | ASP152 |
| A | MN287 |
| A | MN288 |
| A | MN289 |
| A | MN290 |
| A | PO4291 |
| A | HOH293 |
| A | HOH295 |
| A | HOH302 |
| A | HOH309 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE MN B 287 |
| Chain | Residue |
| B | ASP115 |
| B | ASP120 |
| B | ASP152 |
| B | MN288 |
| B | MN290 |
| B | PO4292 |
| B | HOH293 |
| B | HOH294 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN B 288 |
| Chain | Residue |
| B | ASP120 |
| B | MN287 |
| B | PO4292 |
| B | HOH293 |
| B | HOH295 |
| B | HOH296 |
| B | HOH297 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MN B 289 |
| Chain | Residue |
| B | PO4292 |
| B | HOH298 |
| B | HOH299 |
| B | HOH300 |
| B | GLU58 |
| B | PO4291 |
| site_id | ASA |
| Number of Residues | 14 |
| Details | ACTIVE SITE A. |
| Chain | Residue |
| A | GLU48 |
| A | ASP147 |
| A | ASP152 |
| A | LYS154 |
| A | TYR192 |
| A | LYS193 |
| A | LYS56 |
| A | GLU58 |
| A | ARG78 |
| A | TYR89 |
| A | TYR93 |
| A | ASP115 |
| A | ASP117 |
| A | ASP120 |
| site_id | ASB |
| Number of Residues | 14 |
| Details | ACTIVE SITE B. |
| Chain | Residue |
| B | GLU48 |
| B | LYS56 |
| B | GLU58 |
| B | ARG78 |
| B | TYR89 |
| B | TYR93 |
| B | ASP115 |
| B | ASP117 |
| B | ASP120 |
| B | ASP147 |
| B | ASP152 |
| B | LYS154 |
| B | TYR192 |
| B | LYS193 |
| site_id | BC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE MN B 290 |
| Chain | Residue |
| B | ASP147 |
| B | ASP152 |
| B | MN287 |
| B | PO4291 |
| B | PO4292 |
| B | HOH301 |
| B | HOH302 |
| site_id | BC2 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE PO4 B 291 |
| Chain | Residue |
| B | LYS56 |
| B | GLU58 |
| B | ARG78 |
| B | ASP147 |
| B | TYR192 |
| B | LYS193 |
| B | MN289 |
| B | MN290 |
| B | PO4292 |
| B | HOH299 |
| B | HOH396 |
| B | HOH417 |
| site_id | BC3 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE PO4 B 292 |
| Chain | Residue |
| B | LYS56 |
| B | GLU58 |
| B | TYR93 |
| B | ASP120 |
| B | ASP152 |
| B | MN287 |
| B | MN288 |
| B | MN289 |
| B | MN290 |
| B | PO4291 |
| B | HOH293 |
| B | HOH297 |
| B | HOH302 |
| B | HOH310 |
Functional Information from PROSITE/UniProt
| site_id | PS00387 |
| Number of Residues | 7 |
| Details | PPASE Inorganic pyrophosphatase signature. DNDPIDV |
| Chain | Residue | Details |
| A | ASP115-VAL121 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ILE90 | |
| B | ILE90 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | PHE79 | |
| A | ASN116 | |
| A | VAL121 | |
| A | TRP153 | |
| B | PHE79 | |
| B | ASN116 | |
| B | VAL121 | |
| B | TRP153 | |
| Chain | Residue | Details |
| A | LEU65 | |
| B | LEU65 | |
| Chain | Residue | Details |
| A | PRO251 | |
| B | PRO251 | |
| Chain | Residue | Details |
| A | LEU266 | |
| B | LEU266 | |
| Chain | Residue | Details |
| A | VAL286 | |
| B | VAL286 | |
| site_id | SWS_FT_FI7 |
| Number of Residues | 6 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0007744|PubMed:22106047 |
| Chain | Residue | Details |
| A | GLY239 | |
| A | TRP279 | |
| B | GLY239 | |
| B | TRP279 | |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1wgi |
| Chain | Residue | Details |
| A | ASP117 | |
| site_id | CSA2 |
| Number of Residues | 1 |
| Details | Annotated By Reference To The Literature 1wgi |
| Chain | Residue | Details |
| B | ASP117 | |
