1WES

Solution structure of PHD domain in inhibitor of growth family, member 1-like

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003682	molecular_function	chromatin binding
A	0005634	cellular_component	nucleus
A	0006325	biological_process	chromatin organization
A	0008285	biological_process	negative regulation of cell population proliferation
A	0042981	biological_process	regulation of apoptotic process
A	2000772	biological_process	regulation of cellular senescence

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 201

Chain	Residue
A	CYS19
A	CYS21
A	HIS43
A	CYS46

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN A 401

Chain	Residue
A	CYS32
A	CYS37
A	CYS59
A	CYS62

---

Functional Information from PROSITE/UniProt

site_id	PS01359
Number of Residues	44
Details	ZF_PHD_1 Zinc finger PHD-type signature. Cl.Cnqvsygem.....................................IgCdneqCpiewFHfsCvsltykpkgk...................................WyCpkC

Chain	Residue	Details
A	CYS19-CYS62

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	49
Details	Zinc finger: {"description":"PHD-type","evidences":[{"source":"PROSITE-ProRule","id":"PRU00146","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"UniProtKB","id":"Q9UK53","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	Site: {"description":"Histone H3K4me3 binding","evidences":[{"source":"UniProtKB","id":"Q9UK53","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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