1WD2

Solution Structure of the C-terminal RING from a RING-IBR-RING (TRIAD) motif

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004842	molecular_function	ubiquitin-protein transferase activity
A	0008270	molecular_function	zinc ion binding
A	0016567	biological_process	protein ubiquitination

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN A 71

Chain	Residue
A	CYS19
A	CYS22
A	CYS37
A	CYS42
A	PHE46

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	31
Details	ZN_FING: RING-type 2; atypical => ECO:0000255|PROSITE-ProRule:PRU01221

Chain	Residue	Details
A	CYS19-CYS50

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: ACT_SITE => ECO:0000255|PROSITE-ProRule:PRU01221, ECO:0000269|PubMed:21532592, ECO:0000269|PubMed:23707686

Chain	Residue	Details
A	CYS32

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site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01221, ECO:0000269|PubMed:15236971, ECO:0000269|PubMed:23707686, ECO:0000269|PubMed:24058416, ECO:0007744|PDB:1WD2, ECO:0007744|PDB:2M9Y, ECO:0007744|PDB:4KBL, ECO:0007744|PDB:4KC9

Chain	Residue	Details
A	CYS19
A	CYS22
A	CYS37
A	CYS42

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site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01221, ECO:0000269|PubMed:23707686, ECO:0000269|PubMed:24058416, ECO:0007744|PDB:2M9Y, ECO:0007744|PDB:4KBL, ECO:0007744|PDB:4KC9

Chain	Residue	Details
A	CYS47
A	CYS50
A	HIS57
A	CYS64

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