1WAB
PLATELET-ACTIVATING FACTOR ACETYLHYDROLASE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003847 | molecular_function | 1-alkyl-2-acetylglycerophosphocholine esterase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0006629 | biological_process | lipid metabolic process |
| A | 0007283 | biological_process | spermatogenesis |
| A | 0008247 | cellular_component | 1-alkyl-2-acetylglycerophosphocholine esterase complex |
| A | 0016042 | biological_process | lipid catabolic process |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0042803 | molecular_function | protein homodimerization activity |
| A | 0046982 | molecular_function | protein heterodimerization activity |
| A | 0047179 | molecular_function | platelet-activating factor acetyltransferase activity |
| A | 0052689 | molecular_function | carboxylic ester hydrolase activity |
| A | 1902494 | cellular_component | catalytic complex |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE ACT A 300 |
| Chain | Residue |
| A | HOH382 |
| A | ASP46 |
| A | SER47 |
| A | GLY73 |
| A | GLY74 |
| A | ASN104 |
| A | HIS195 |
| site_id | CAT |
| Number of Residues | 3 |
| Details |
| Chain | Residue |
| A | SER47 |
| A | HIS195 |
| A | ASP192 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Active site: {"evidences":[{"source":"PubMed","id":"8985254","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1BWP","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 5 |
| Details | Annotated By Reference To The Literature 1bwp |
| Chain | Residue | Details |
| A | ASP192 | |
| A | ASN104 | |
| A | SER47 | |
| A | HIS195 | |
| A | GLY74 |
| site_id | MCSA1 |
| Number of Residues | 5 |
| Details | M-CSA 94 |
| Chain | Residue | Details |
| A | SER47 | covalently attached, hydrogen bond acceptor, hydrogen bond donor, nucleofuge, nucleophile, proton acceptor, proton donor |
| A | GLY74 | electrostatic stabiliser, hydrogen bond donor |
| A | ASN104 | electrostatic stabiliser, hydrogen bond donor |
| A | ASP192 | activator, electrostatic stabiliser, hydrogen bond acceptor |
| A | HIS195 | electrostatic stabiliser, hydrogen bond acceptor, hydrogen bond donor, proton acceptor, proton donor |
