1W8S
The mechanism of the Schiff Base Forming Fructose-1,6-bisphosphate Aldolase: Structural analysis of reaction intermediates
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0003824 | molecular_function | catalytic activity |
A | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
A | 0005737 | cellular_component | cytoplasm |
A | 0006096 | biological_process | glycolytic process |
A | 0016829 | molecular_function | lyase activity |
B | 0003824 | molecular_function | catalytic activity |
B | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
B | 0005737 | cellular_component | cytoplasm |
B | 0006096 | biological_process | glycolytic process |
B | 0016829 | molecular_function | lyase activity |
C | 0003824 | molecular_function | catalytic activity |
C | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
C | 0005737 | cellular_component | cytoplasm |
C | 0006096 | biological_process | glycolytic process |
C | 0016829 | molecular_function | lyase activity |
D | 0003824 | molecular_function | catalytic activity |
D | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
D | 0005737 | cellular_component | cytoplasm |
D | 0006096 | biological_process | glycolytic process |
D | 0016829 | molecular_function | lyase activity |
E | 0003824 | molecular_function | catalytic activity |
E | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
E | 0005737 | cellular_component | cytoplasm |
E | 0006096 | biological_process | glycolytic process |
E | 0016829 | molecular_function | lyase activity |
F | 0003824 | molecular_function | catalytic activity |
F | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
F | 0005737 | cellular_component | cytoplasm |
F | 0006096 | biological_process | glycolytic process |
F | 0016829 | molecular_function | lyase activity |
G | 0003824 | molecular_function | catalytic activity |
G | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
G | 0005737 | cellular_component | cytoplasm |
G | 0006096 | biological_process | glycolytic process |
G | 0016829 | molecular_function | lyase activity |
H | 0003824 | molecular_function | catalytic activity |
H | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
H | 0005737 | cellular_component | cytoplasm |
H | 0006096 | biological_process | glycolytic process |
H | 0016829 | molecular_function | lyase activity |
I | 0003824 | molecular_function | catalytic activity |
I | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
I | 0005737 | cellular_component | cytoplasm |
I | 0006096 | biological_process | glycolytic process |
I | 0016829 | molecular_function | lyase activity |
J | 0003824 | molecular_function | catalytic activity |
J | 0004332 | molecular_function | fructose-bisphosphate aldolase activity |
J | 0005737 | cellular_component | cytoplasm |
J | 0006096 | biological_process | glycolytic process |
J | 0016829 | molecular_function | lyase activity |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 10 |
Details | ACT_SITE: Proton donor |
Chain | Residue | Details |
A | PHE146 | |
J | PHE146 | |
B | PHE146 | |
C | PHE146 | |
D | PHE146 | |
E | PHE146 | |
F | PHE146 | |
G | PHE146 | |
H | PHE146 | |
I | PHE146 |
site_id | SWS_FT_FI2 |
Number of Residues | 10 |
Details | ACT_SITE: Schiff-base intermediate with dihydroxyacetone-P |
Chain | Residue | Details |
A | LYS177 | |
J | LYS177 | |
B | LYS177 | |
C | LYS177 | |
D | LYS177 | |
E | LYS177 | |
F | LYS177 | |
G | LYS177 | |
H | LYS177 | |
I | LYS177 |
site_id | SWS_FT_FI3 |
Number of Residues | 80 |
Details | BINDING: |
Chain | Residue | Details |
A | ASP24 | |
B | HIS29 | |
B | ASP33 | |
B | GLU144 | |
B | ARG148 | |
B | LYS177 | |
B | SER202 | |
B | GLY231 | |
C | ASP24 | |
C | HIS29 | |
C | ASP33 | |
A | HIS29 | |
C | GLU144 | |
C | ARG148 | |
C | LYS177 | |
C | SER202 | |
C | GLY231 | |
D | ASP24 | |
D | HIS29 | |
D | ASP33 | |
D | GLU144 | |
D | ARG148 | |
A | ASP33 | |
D | LYS177 | |
D | SER202 | |
D | GLY231 | |
E | ASP24 | |
E | HIS29 | |
E | ASP33 | |
E | GLU144 | |
E | ARG148 | |
E | LYS177 | |
E | SER202 | |
A | GLU144 | |
E | GLY231 | |
F | ASP24 | |
F | HIS29 | |
F | ASP33 | |
F | GLU144 | |
F | ARG148 | |
F | LYS177 | |
F | SER202 | |
F | GLY231 | |
G | ASP24 | |
A | ARG148 | |
G | HIS29 | |
G | ASP33 | |
G | GLU144 | |
G | ARG148 | |
G | LYS177 | |
G | SER202 | |
G | GLY231 | |
H | ASP24 | |
H | HIS29 | |
H | ASP33 | |
A | LYS177 | |
H | GLU144 | |
H | ARG148 | |
H | LYS177 | |
H | SER202 | |
H | GLY231 | |
I | ASP24 | |
I | HIS29 | |
I | ASP33 | |
I | GLU144 | |
I | ARG148 | |
A | SER202 | |
I | LYS177 | |
I | SER202 | |
I | GLY231 | |
J | ASP24 | |
J | HIS29 | |
J | ASP33 | |
J | GLU144 | |
J | ARG148 | |
J | LYS177 | |
J | SER202 | |
A | GLY231 | |
J | GLY231 | |
B | ASP24 |
Catalytic Information from CSA
site_id | CSA1 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ok4 |
Chain | Residue | Details |
A | ASP24 | |
A | LYS177 | |
A | PHE146 |
site_id | CSA10 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ok4 |
Chain | Residue | Details |
J | ASP24 | |
J | LYS177 | |
J | PHE146 |
site_id | CSA2 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ok4 |
Chain | Residue | Details |
B | ASP24 | |
B | LYS177 | |
B | PHE146 |
site_id | CSA3 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ok4 |
Chain | Residue | Details |
C | ASP24 | |
C | LYS177 | |
C | PHE146 |
site_id | CSA4 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ok4 |
Chain | Residue | Details |
D | ASP24 | |
D | LYS177 | |
D | PHE146 |
site_id | CSA5 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ok4 |
Chain | Residue | Details |
E | ASP24 | |
E | LYS177 | |
E | PHE146 |
site_id | CSA6 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ok4 |
Chain | Residue | Details |
F | ASP24 | |
F | LYS177 | |
F | PHE146 |
site_id | CSA7 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ok4 |
Chain | Residue | Details |
G | ASP24 | |
G | LYS177 | |
G | PHE146 |
site_id | CSA8 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ok4 |
Chain | Residue | Details |
H | ASP24 | |
H | LYS177 | |
H | PHE146 |
site_id | CSA9 |
Number of Residues | 3 |
Details | Annotated By Reference To The Literature 1ok4 |
Chain | Residue | Details |
I | ASP24 | |
I | LYS177 | |
I | PHE146 |