Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0015035 | molecular_function | protein-disulfide reductase activity |
| B | 0015035 | molecular_function | protein-disulfide reductase activity |
| C | 0015035 | molecular_function | protein-disulfide reductase activity |
| D | 0015035 | molecular_function | protein-disulfide reductase activity |
| E | 0015035 | molecular_function | protein-disulfide reductase activity |
| F | 0015035 | molecular_function | protein-disulfide reductase activity |
Functional Information from PROSITE/UniProt
| site_id | PS00194 |
| Number of Residues | 19 |
| Details | THIOREDOXIN_1 Thioredoxin family active site. VVdFHaqWCGPCKiLgprL |
| Chain | Residue | Details |
| A | VAL23-LEU41 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 630 |
| Details | Domain: {"description":"Thioredoxin","evidences":[{"source":"PROSITE-ProRule","id":"PRU00691","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 12 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"UniProtKB","id":"P10599","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 6 |
| Details | Site: {"description":"Deprotonates C-terminal active site Cys","evidences":[{"source":"UniProtKB","id":"P10599","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Site: {"description":"Contributes to redox potential value","evidences":[{"source":"UniProtKB","id":"P10599","evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Modified residue: {"description":"N6-succinyllysine; alternate","evidences":[{"source":"UniProtKB","id":"P97493","evidenceCode":"ECO:0000250"}]} |
Catalytic Information from CSA
| site_id | CSA1 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1mek |
| Chain | Residue | Details |
| A | CYS31 | |
| A | CYS34 | |
| A | PRO33 | |
| A | GLY32 | |
| site_id | CSA10 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1mek |
| Chain | Residue | Details |
| D | CYS31 | |
| D | CYS34 | |
| site_id | CSA11 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1mek |
| Chain | Residue | Details |
| E | CYS31 | |
| E | CYS34 | |
| site_id | CSA12 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1mek |
| Chain | Residue | Details |
| F | CYS31 | |
| F | CYS34 | |
| site_id | CSA2 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1mek |
| Chain | Residue | Details |
| B | CYS31 | |
| B | CYS34 | |
| B | PRO33 | |
| B | GLY32 | |
| site_id | CSA3 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1mek |
| Chain | Residue | Details |
| C | CYS31 | |
| C | CYS34 | |
| C | PRO33 | |
| C | GLY32 | |
| site_id | CSA4 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1mek |
| Chain | Residue | Details |
| D | CYS31 | |
| D | CYS34 | |
| D | PRO33 | |
| D | GLY32 | |
| site_id | CSA5 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1mek |
| Chain | Residue | Details |
| E | CYS31 | |
| E | CYS34 | |
| E | PRO33 | |
| E | GLY32 | |
| site_id | CSA6 |
| Number of Residues | 4 |
| Details | Annotated By Reference To The Literature 1mek |
| Chain | Residue | Details |
| F | CYS31 | |
| F | CYS34 | |
| F | PRO33 | |
| F | GLY32 | |
| site_id | CSA7 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1mek |
| Chain | Residue | Details |
| A | CYS31 | |
| A | CYS34 | |
| site_id | CSA8 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1mek |
| Chain | Residue | Details |
| B | CYS31 | |
| B | CYS34 | |
| site_id | CSA9 |
| Number of Residues | 2 |
| Details | Annotated By Reference To The Literature 1mek |
| Chain | Residue | Details |
| C | CYS31 | |
| C | CYS34 | |
