1W7Z
Crystal structure of the free (uncomplexed) Ecballium elaterium trypsin inhibitor (EETI-II)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004866 | molecular_function | endopeptidase inhibitor activity |
| A | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
| A | 0005576 | cellular_component | extracellular region |
| B | 0004866 | molecular_function | endopeptidase inhibitor activity |
| B | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
| B | 0005576 | cellular_component | extracellular region |
| C | 0004866 | molecular_function | endopeptidase inhibitor activity |
| C | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
| C | 0005576 | cellular_component | extracellular region |
| D | 0004866 | molecular_function | endopeptidase inhibitor activity |
| D | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
| D | 0005576 | cellular_component | extracellular region |
| E | 0004866 | molecular_function | endopeptidase inhibitor activity |
| E | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
| E | 0005576 | cellular_component | extracellular region |
| F | 0004866 | molecular_function | endopeptidase inhibitor activity |
| F | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
| F | 0005576 | cellular_component | extracellular region |
| G | 0004866 | molecular_function | endopeptidase inhibitor activity |
| G | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
| G | 0005576 | cellular_component | extracellular region |
| H | 0004866 | molecular_function | endopeptidase inhibitor activity |
| H | 0004867 | molecular_function | serine-type endopeptidase inhibitor activity |
| H | 0005576 | cellular_component | extracellular region |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA A1032 |
| Chain | Residue |
| A | SER13 |
| A | CYS15 |
| B | SER13 |
| B | ASP14 |
| B | CYS15 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE NA C1032 |
| Chain | Residue |
| D | CYS15 |
| C | SER13 |
| C | ASP14 |
| C | CYS15 |
| D | SER13 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE NA E1031 |
| Chain | Residue |
| E | SER13 |
| E | CYS15 |
| F | SER13 |
| F | CYS15 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT B1032 |
| Chain | Residue |
| B | ARG8 |
| F | LEU6 |
| G | ARG4 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE FMT D1032 |
| Chain | Residue |
| B | LEU6 |
| D | ARG8 |
| G | ILE5 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE FMT F1032 |
| Chain | Residue |
| F | ARG8 |
| F | HOH2019 |
| G | LEU16 |
| G | ALA17 |
Functional Information from PROSITE/UniProt
| site_id | PS00286 |
| Number of Residues | 20 |
| Details | SQUASH_INHIBITOR Squash family of serine protease inhibitors signature. CPrilirCkqDsDClagCvC |
| Chain | Residue | Details |
| A | CYS2-CYS21 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 232 |
| Details | Peptide: {"description":"Trypsin inhibitor 2","featureId":"PRO_0000044381"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | Site: {"description":"Reactive bond"} |
| Chain | Residue | Details |
