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1W7P

The crystal structure of endosomal complex ESCRT-II (VPS22/VPS25/VPS36)

Functional Information from GO Data
ChainGOidnamespacecontents
A0000122biological_processnegative regulation of transcription by RNA polymerase II
A0000814cellular_componentESCRT II complex
A0003674molecular_functionmolecular_function
A0005515molecular_functionprotein binding
A0005737cellular_componentcytoplasm
A0006623biological_processprotein targeting to vacuole
A0006886biological_processintracellular protein transport
A0007034biological_processvacuolar transport
A0008289molecular_functionlipid binding
A0010008cellular_componentendosome membrane
A0015031biological_processprotein transport
A0043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
A0043328biological_processprotein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
A0071985biological_processmultivesicular body sorting pathway
A0072665biological_processprotein localization to vacuole
A0072666biological_processestablishment of protein localization to vacuole
A1904669biological_processATP export
B0000122biological_processnegative regulation of transcription by RNA polymerase II
B0000814cellular_componentESCRT II complex
B0005198molecular_functionstructural molecule activity
B0005515molecular_functionprotein binding
B0005737cellular_componentcytoplasm
B0005829cellular_componentcytosol
B0006623biological_processprotein targeting to vacuole
B0010008cellular_componentendosome membrane
B0015031biological_processprotein transport
B0042803molecular_functionprotein homodimerization activity
B0043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
B0043328biological_processprotein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
B0071985biological_processmultivesicular body sorting pathway
B1904669biological_processATP export
C0000122biological_processnegative regulation of transcription by RNA polymerase II
C0000814cellular_componentESCRT II complex
C0005198molecular_functionstructural molecule activity
C0005515molecular_functionprotein binding
C0005737cellular_componentcytoplasm
C0005829cellular_componentcytosol
C0006623biological_processprotein targeting to vacuole
C0010008cellular_componentendosome membrane
C0015031biological_processprotein transport
C0042803molecular_functionprotein homodimerization activity
C0043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
C0043328biological_processprotein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
C0071985biological_processmultivesicular body sorting pathway
C1904669biological_processATP export
D0000122biological_processnegative regulation of transcription by RNA polymerase II
D0000814cellular_componentESCRT II complex
D0005515molecular_functionprotein binding
D0005737cellular_componentcytoplasm
D0006623biological_processprotein targeting to vacuole
D0008270molecular_functionzinc ion binding
D0010008cellular_componentendosome membrane
D0015031biological_processprotein transport
D0016236biological_processmacroautophagy
D0031902cellular_componentlate endosome membrane
D0032258biological_processcytoplasm to vacuole targeting by the Cvt pathway
D0032266molecular_functionphosphatidylinositol-3-phosphate binding
D0032509biological_processendosome transport via multivesicular body sorting pathway
D0043130molecular_functionubiquitin binding
D0043162biological_processubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
D0043328biological_processprotein transport to vacuole involved in ubiquitin-dependent protein catabolic process via the multivesicular body sorting pathway
D0045053biological_processprotein retention in Golgi apparatus
D0046872molecular_functionmetal ion binding
D1904669biological_processATP export
Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues23
DetailsCoiled coil: {"evidences":[{"evidenceCode":"ECO:0000255"}]}
ChainResidueDetails

246905

PDB entries from 2025-12-31

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