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1W70

SH3 domain of p40phox complexed with C-terminal polyProline region of p47phox

Functional Information from GO Data
ChainGOidnamespacecontents
A0006909biological_processphagocytosis
A0016176molecular_functionsuperoxide-generating NADPH oxidase activator activity
A0043020cellular_componentNADPH oxidase complex
A0045730biological_processrespiratory burst
B0006909biological_processphagocytosis
B0016176molecular_functionsuperoxide-generating NADPH oxidase activator activity
B0043020cellular_componentNADPH oxidase complex
B0045730biological_processrespiratory burst
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 A1229
ChainResidue
ALYS171
AHIS172
AHOH2083
AHOH2084
AHOH2085

site_idAC2
Number of Residues4
DetailsBINDING SITE FOR RESIDUE SO4 B1229
ChainResidue
BARG202
BASN204
BLYS205
BHOH2081

site_idAC3
Number of Residues11
DetailsBINDING SITE FOR RESIDUE SO4 B1230
ChainResidue
BILE170
BLYS171
BHIS172
BARG174
BPHE198
BHOH2045
BHOH2082
BHOH2083
BHOH2084
BHOH2086
BHOH2087

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 B1231
ChainResidue
ALYS192
ALYS205
BARG174
BPHE198
BHOH2088

site_idAC5
Number of Residues9
DetailsBINDING SITE FOR RESIDUE TFA B1232
ChainResidue
ALEU187
AILE203
AILE218
BLEU169
BILE170
BSER201
BARG202
BHOH2089
CPRO369

site_idAC6
Number of Residues7
DetailsBINDING SITE FOR RESIDUE TFA B1233
ChainResidue
AILE170
AARG202
BLEU187
BILE218
BHOH2090
DPRO369
DSER370

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PDB entries from 2024-12-25

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