Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

1W5E

FtsZ W319Y mutant, P1 (M. jannaschii)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0003924	molecular_function	GTPase activity
A	0005525	molecular_function	GTP binding
A	0005737	cellular_component	cytoplasm
A	0032153	cellular_component	cell division site
A	0043093	biological_process	FtsZ-dependent cytokinesis
A	0051258	biological_process	protein polymerization
A	0051301	biological_process	cell division
B	0000166	molecular_function	nucleotide binding
B	0003924	molecular_function	GTPase activity
B	0005525	molecular_function	GTP binding
B	0005737	cellular_component	cytoplasm
B	0032153	cellular_component	cell division site
B	0043093	biological_process	FtsZ-dependent cytokinesis
B	0051258	biological_process	protein polymerization
B	0051301	biological_process	cell division
C	0000166	molecular_function	nucleotide binding
C	0003924	molecular_function	GTPase activity
C	0005525	molecular_function	GTP binding
C	0005737	cellular_component	cytoplasm
C	0032153	cellular_component	cell division site
C	0043093	biological_process	FtsZ-dependent cytokinesis
C	0051258	biological_process	protein polymerization
C	0051301	biological_process	cell division
D	0000166	molecular_function	nucleotide binding
D	0003924	molecular_function	GTPase activity
D	0005525	molecular_function	GTP binding
D	0005737	cellular_component	cytoplasm
D	0032153	cellular_component	cell division site
D	0043093	biological_process	FtsZ-dependent cytokinesis
D	0051258	biological_process	protein polymerization
D	0051301	biological_process	cell division
E	0000166	molecular_function	nucleotide binding
E	0003924	molecular_function	GTPase activity
E	0005525	molecular_function	GTP binding
E	0005737	cellular_component	cytoplasm
E	0032153	cellular_component	cell division site
E	0043093	biological_process	FtsZ-dependent cytokinesis
E	0051258	biological_process	protein polymerization
E	0051301	biological_process	cell division
F	0000166	molecular_function	nucleotide binding
F	0003924	molecular_function	GTPase activity
F	0005525	molecular_function	GTP binding
F	0005737	cellular_component	cytoplasm
F	0032153	cellular_component	cell division site
F	0043093	biological_process	FtsZ-dependent cytokinesis
F	0051258	biological_process	protein polymerization
F	0051301	biological_process	cell division
G	0000166	molecular_function	nucleotide binding
G	0003924	molecular_function	GTPase activity
G	0005525	molecular_function	GTP binding
G	0005737	cellular_component	cytoplasm
G	0032153	cellular_component	cell division site
G	0043093	biological_process	FtsZ-dependent cytokinesis
G	0051258	biological_process	protein polymerization
G	0051301	biological_process	cell division
H	0000166	molecular_function	nucleotide binding
H	0003924	molecular_function	GTPase activity
H	0005525	molecular_function	GTP binding
H	0005737	cellular_component	cytoplasm
H	0032153	cellular_component	cell division site
H	0043093	biological_process	FtsZ-dependent cytokinesis
H	0051258	biological_process	protein polymerization
H	0051301	biological_process	cell division
I	0000166	molecular_function	nucleotide binding
I	0003924	molecular_function	GTPase activity
I	0005525	molecular_function	GTP binding
I	0005737	cellular_component	cytoplasm
I	0032153	cellular_component	cell division site
I	0043093	biological_process	FtsZ-dependent cytokinesis
I	0051258	biological_process	protein polymerization
I	0051301	biological_process	cell division

Functional Information from PDB Data

site_id	AC1
Number of Residues	20
Details	BINDING SITE FOR RESIDUE GTP A 500

Chain	Residue
A	GLY46
A	GLY134
A	THR135
A	GLY136
A	GLU165
A	ARG169
A	PHE208
A	ALA211
A	ASP212
A	HOH2029
A	HOH2074
A	GLY47
A	HOH2076
A	ALA48
A	GLY96
A	ALA97
A	GLY98
A	GLY99
A	GLY130
A	GLY133

site_id	AC2
Number of Residues	20
Details	BINDING SITE FOR RESIDUE GTP B 500

Chain	Residue
B	GLY46
B	GLY47
B	ALA48
B	GLY96
B	ALA97
B	GLY98
B	GLY99
B	GLY130
B	LEU131
B	GLY133
B	GLY134
B	THR135
B	GLY136
B	GLU165
B	ARG169
B	PHE208
B	ALA211
B	ASP212
B	HOH2012
B	HOH2013

site_id	AC3
Number of Residues	20
Details	BINDING SITE FOR RESIDUE GTP C 500

Chain	Residue
C	GLY46
C	GLY47
C	ALA48
C	ALA97
C	GLY99
C	GLY130
C	LEU131
C	GLY133
C	GLY134
C	THR135
C	GLY136
C	PRO161
C	GLU165
C	ARG169
C	PHE208
C	ALA211
C	ASP212
C	HOH2030
C	HOH2031
C	HOH2035

site_id	AC4
Number of Residues	23
Details	BINDING SITE FOR RESIDUE GTP D 500

Chain	Residue
D	GLY46
D	GLY47
D	ALA48
D	ASN51
D	ALA97
D	GLY98
D	GLY99
D	GLY130
D	LEU131
D	GLY133
D	GLY134
D	THR135
D	GLY136
D	GLU165
D	ARG169
D	PHE208
D	ALA211
D	ASP212
D	HOH2023
D	HOH2027
D	HOH2028
D	HOH2029
D	HOH2079

site_id	AC5
Number of Residues	20
Details	BINDING SITE FOR RESIDUE GTP E 500

Chain	Residue
E	HOH2015
E	HOH2016
E	HOH2017
E	HOH2052
E	GLY46
E	GLY47
E	ALA48
E	ALA97
E	GLY99
E	GLY130
E	LEU131
E	GLY133
E	GLY134
E	THR135
E	GLY136
E	GLU165
E	ARG169
E	PHE208
E	ALA211
E	ASP212

site_id	AC6
Number of Residues	18
Details	BINDING SITE FOR RESIDUE GTP F 500

Chain	Residue
F	GLY46
F	GLY47
F	ALA48
F	ALA97
F	GLY99
F	GLY130
F	LEU131
F	GLY133
F	GLY134
F	THR135
F	GLY136
F	GLU165
F	ARG169
F	PHE208
F	ALA211
F	ASP212
F	HOH2034
F	HOH2087

site_id	AC7
Number of Residues	19
Details	BINDING SITE FOR RESIDUE GTP G 500

Chain	Residue
G	GLY46
G	GLY47
G	ALA48
G	ASN51
G	GLY96
G	ALA97
G	GLY98
G	GLY99
G	GLY130
G	GLY133
G	GLY134
G	THR135
G	GLY136
G	GLU165
G	ARG169
G	PHE208
G	ALA211
G	ASP212
G	HOH2079

site_id	AC8
Number of Residues	20
Details	BINDING SITE FOR RESIDUE GTP H 500

Chain	Residue
H	GLY46
H	GLY47
H	ALA48
H	GLY96
H	ALA97
H	GLY98
H	GLY99
H	GLY130
H	LEU131
H	GLY133
H	GLY134
H	THR135
H	GLY136
H	GLU165
H	ARG169
H	PHE208
H	ALA211
H	ASP212
H	HOH2011
H	HOH2024

site_id	AC9
Number of Residues	19
Details	BINDING SITE FOR RESIDUE GTP I 500

Chain	Residue
I	GLY46
I	GLY47
I	ALA48
I	GLY96
I	ALA97
I	GLY98
I	GLY99
I	GLY130
I	LEU131
I	GLY133
I	GLY134
I	THR135
I	GLY136
I	GLU165
I	ARG169
I	PHE208
I	ALA211
I	ASP212
I	HOH2052

Functional Information from PROSITE/UniProt

site_id	PS01134
Number of Residues	35
Details	FTSZ_1 FtsZ protein signature 1. NTDaQqLirtkadkkiligkkltr.GlGAGGnPkiG

Chain	Residue	Details
A	ASN70-GLY104

site_id	PS01135
Number of Residues	22
Details	FTSZ_2 FtsZ protein signature 2. DMvFITCGlGGGTGTGSAPVVA

Chain	Residue	Details
A	ASP123-ALA144

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15558053","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17900614","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9428770","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI2
Number of Residues	18
Details	Binding site: {"evidences":[{"source":"PubMed","id":"15558053","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI3
Number of Residues	36
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00909","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15558053","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17900614","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9428770","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

site_id	SWS_FT_FI4
Number of Residues	9
Details	Binding site: {"evidences":[{"source":"HAMAP-Rule","id":"MF_00909","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"15558053","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"9428770","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)