1W2Z

PSAO and Xenon

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005507	molecular_function	copper ion binding
A	0008131	molecular_function	primary amine oxidase activity
A	0009308	biological_process	amine metabolic process
A	0016491	molecular_function	oxidoreductase activity
A	0046872	molecular_function	metal ion binding
A	0048038	molecular_function	quinone binding
A	0052595	molecular_function	aliphatic amine oxidase activity
A	0052597	molecular_function	diamine oxidase activity
B	0005507	molecular_function	copper ion binding
B	0008131	molecular_function	primary amine oxidase activity
B	0009308	biological_process	amine metabolic process
B	0016491	molecular_function	oxidoreductase activity
B	0046872	molecular_function	metal ion binding
B	0048038	molecular_function	quinone binding
B	0052595	molecular_function	aliphatic amine oxidase activity
B	0052597	molecular_function	diamine oxidase activity
C	0005507	molecular_function	copper ion binding
C	0008131	molecular_function	primary amine oxidase activity
C	0009308	biological_process	amine metabolic process
C	0016491	molecular_function	oxidoreductase activity
C	0046872	molecular_function	metal ion binding
C	0048038	molecular_function	quinone binding
C	0052595	molecular_function	aliphatic amine oxidase activity
C	0052597	molecular_function	diamine oxidase activity
D	0005507	molecular_function	copper ion binding
D	0008131	molecular_function	primary amine oxidase activity
D	0009308	biological_process	amine metabolic process
D	0016491	molecular_function	oxidoreductase activity
D	0046872	molecular_function	metal ion binding
D	0048038	molecular_function	quinone binding
D	0052595	molecular_function	aliphatic amine oxidase activity
D	0052597	molecular_function	diamine oxidase activity

Functional Information from PROSITE/UniProt

site_id	PS01164
Number of Residues	14
Details	COPPER_AMINE_OXID_1 Copper amine oxidase topaquinone signature. LIVrtivTvgNYDN

Chain	Residue	Details
A	LEU376-ASN389

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton acceptor => ECO:0000250|UniProtKB:P12807

Chain	Residue	Details
A	ASP300
B	ASP300
C	ASP300
D	ASP300

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	ACT_SITE: Schiff-base intermediate with substrate; via topaquinone => ECO:0000250|UniProtKB:P12807

Chain	Residue	Details
A	TPQ387
B	TPQ387
C	TPQ387
D	TPQ387

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P12807

Chain	Residue	Details
A	PHE298
B	PHE298
C	PHE298
D	PHE298

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250|UniProtKB:P46883

Chain	Residue	Details
A	VAL384
B	VAL384
C	VAL384
D	VAL384

---

site_id	SWS_FT_FI5
Number of Residues	32
Details	BINDING: BINDING => ECO:0000269|PubMed:8805580, ECO:0007744|PDB:1KSI

Chain	Residue	Details
A	HIS442
B	HIS444
B	ASP451
B	PHE452
B	ASP453
B	ASP592
B	ILE593
B	HIS603
C	HIS442
C	HIS444
C	ASP451
A	HIS444
C	PHE452
C	ASP453
C	ASP592
C	ILE593
C	HIS603
D	HIS442
D	HIS444
D	ASP451
D	PHE452
D	ASP453
A	ASP451
D	ASP592
D	ILE593
D	HIS603
A	PHE452
A	ASP453
A	ASP592
A	ILE593
A	HIS603
B	HIS442

---

site_id	SWS_FT_FI6
Number of Residues	4
Details	MOD_RES: 2',4',5'-topaquinone => ECO:0000269|PubMed:8805580, ECO:0007744|PDB:1KSI

Chain	Residue	Details
A	TPQ387
B	TPQ387
C	TPQ387
D	TPQ387

---

site_id	SWS_FT_FI7
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:8805580, ECO:0007744|PDB:1KSI

Chain	Residue	Details
A	ASN131
B	ASN131
C	ASN131
D	ASN131

---

site_id	SWS_FT_FI8
Number of Residues	4
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000305

Chain	Residue	Details
A	ASN364
B	ASN364
C	ASN364
D	ASN364

---

Catalytic Information from CSA

site_id	CSA1
Number of Residues	1
Details	Annotated By Reference To The Literature 1oac

Chain	Residue	Details
A	ASP300

---

site_id	CSA2
Number of Residues	1
Details	Annotated By Reference To The Literature 1oac

Chain	Residue	Details
B	ASP300

---

site_id	CSA3
Number of Residues	1
Details	Annotated By Reference To The Literature 1oac

Chain	Residue	Details
C	ASP300

---

site_id	CSA4
Number of Residues	1
Details	Annotated By Reference To The Literature 1oac

Chain	Residue	Details
D	ASP300

---